An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy.

An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy.

Macroautophagy is a cellular process whereby the cell sequesters and recycles cytosolic constituents in a lysosome-dependent manner. It has also been implicated in a number of disorders, including cancer and neurodegeneration. Although a previous report that AGS3 over-expression promotes macroautoph...

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Bibliographic Details
Main Authors: Benjamin Groves, Hilde Abrahamsen, Heather Clingan, Michael Frantz, Lauren Mavor, Jeffrey Bailey, Dzwokai Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2811177?pdf=render

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