Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey
Linden honey represents a unique honey variety valued for its nutritional benefits, distinctive taste and aroma. Phenols, polyphenols, flavonoids, ascorbic acid and phenolic acids in honey have antioxidant activities. This study aimed to investigate the effects of linden honey on the activi...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2023-12-01
|
| Series: | Acta Veterinaria |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acve-2023-0035 |
| _version_ | 1797387257105088512 |
|---|---|
| author | Gavrilović Ljubica Stojiljković Vesna Stanić Vojislav Jovanović Dragoljub Pejić Snežana Borović Branka Pajović Snežana B. |
| author_facet | Gavrilović Ljubica Stojiljković Vesna Stanić Vojislav Jovanović Dragoljub Pejić Snežana Borović Branka Pajović Snežana B. |
| author_sort | Gavrilović Ljubica |
| collection | DOAJ |
| description | Linden honey represents a unique honey variety valued for its nutritional benefits, distinctive taste and aroma. Phenols, polyphenols, flavonoids, ascorbic acid and phenolic acids in honey have antioxidant activities. This study aimed to investigate the effects of linden honey on the activities of antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx), as well as on the concentration of malondialdehyde (MDA) in individually housed animals. The investigated parameters were quantified using spectrophotometric method for determination of enzyme activities and MDA concentration in the blood. We found that treatment with linden honey in the socially isolated animals significantly increased the enzyme activities of CAT and GPx, and significantly decreased the concentration of MDA. The modulation of CAT and GPx activities in socially isolated animals treated with linden honey may be very important for understanding the role of honey in the capacity of antioxidant defense system to increase and maintain its stability in psychosocial stress conditions. Our results may be important in biomedical research for understanding the role of honey in the amelioration of oxidative stress. |
| first_indexed | 2024-03-08T22:22:36Z |
| format | Article |
| id | doaj.art-6fbff3ca6ac149ec97bcdf7d8b108a1f |
| institution | Directory Open Access Journal |
| issn | 1820-7448 |
| language | English |
| last_indexed | 2024-03-08T22:22:36Z |
| publishDate | 2023-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Veterinaria |
| spelling | doaj.art-6fbff3ca6ac149ec97bcdf7d8b108a1f2023-12-18T12:44:17ZengSciendoActa Veterinaria1820-74482023-12-0173446447210.2478/acve-2023-0035Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with HoneyGavrilović Ljubica0Stojiljković Vesna1Stanić Vojislav2Jovanović Dragoljub3Pejić Snežana4Borović Branka5Pajović Snežana B.6University of Belgrade, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, Department of Molecular Biology and Endocrinology, Belgrade, SerbiaUniversity of Belgrade, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, Department of Molecular Biology and Endocrinology, Belgrade, SerbiaUniversity of Belgrade, Institute of Nuclear Sciences “Vinča”, National Institute of the Republic of Serbia, Department of Radiation and Environmental Protection, Belgrade, SerbiaUniversity of Belgrade, Faculty of Veterinary Medicine, Belgrade, SerbiaUniversity of Belgrade, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, Department of Molecular Biology and Endocrinology, Belgrade, SerbiaInstitute of Meat Hygiene and Technology, Belgrade, SerbiaUniversity of Belgrade, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, Department of Molecular Biology and Endocrinology, Belgrade, SerbiaLinden honey represents a unique honey variety valued for its nutritional benefits, distinctive taste and aroma. Phenols, polyphenols, flavonoids, ascorbic acid and phenolic acids in honey have antioxidant activities. This study aimed to investigate the effects of linden honey on the activities of antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx), as well as on the concentration of malondialdehyde (MDA) in individually housed animals. The investigated parameters were quantified using spectrophotometric method for determination of enzyme activities and MDA concentration in the blood. We found that treatment with linden honey in the socially isolated animals significantly increased the enzyme activities of CAT and GPx, and significantly decreased the concentration of MDA. The modulation of CAT and GPx activities in socially isolated animals treated with linden honey may be very important for understanding the role of honey in the capacity of antioxidant defense system to increase and maintain its stability in psychosocial stress conditions. Our results may be important in biomedical research for understanding the role of honey in the amelioration of oxidative stress.https://doi.org/10.2478/acve-2023-0035honeybloodsocial isolationenzymes activityantioxidant status |
| spellingShingle | Gavrilović Ljubica Stojiljković Vesna Stanić Vojislav Jovanović Dragoljub Pejić Snežana Borović Branka Pajović Snežana B. Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey Acta Veterinaria honey blood social isolation enzymes activity antioxidant status |
| title | Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey |
| title_full | Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey |
| title_fullStr | Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey |
| title_full_unstemmed | Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey |
| title_short | Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey |
| title_sort | antioxidant status in the blood of psychosocially stressed rats treated with honey |
| topic | honey blood social isolation enzymes activity antioxidant status |
| url | https://doi.org/10.2478/acve-2023-0035 |
| work_keys_str_mv | AT gavrilovicljubica antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT stojiljkovicvesna antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT stanicvojislav antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT jovanovicdragoljub antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT pejicsnezana antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT borovicbranka antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney AT pajovicsnezanab antioxidantstatusinthebloodofpsychosociallystressedratstreatedwithhoney |