Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place

Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiolo...

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Main Authors: Rafiz Abdul Rani, Raja Affendi Raja Ali, Yeong Yeh Lee
Format: Article
Language:English
Published: Korean Association for the Study of Intestinal Diseases 2016-10-01
Series:Intestinal Research
Subjects:
Online Access:http://www.irjournal.org/upload/pdf/ir-14-297.pdf
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author Rafiz Abdul Rani
Raja Affendi Raja Ali
Yeong Yeh Lee
author_facet Rafiz Abdul Rani
Raja Affendi Raja Ali
Yeong Yeh Lee
author_sort Rafiz Abdul Rani
collection DOAJ
description Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm.
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spelling doaj.art-6fc1cc53440a40a39ba877324da4cad12022-12-21T23:40:15ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562016-10-0114429730410.5217/ir.2016.14.4.297165Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into placeRafiz Abdul Rani0Raja Affendi Raja Ali1Yeong Yeh Lee2Gastroenterology Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia.Gastroenterology Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm.http://www.irjournal.org/upload/pdf/ir-14-297.pdfIrritable bowel syndromeInflammatory bowel diseaseGut-brain axisIBS-IBD overlap syndrome
spellingShingle Rafiz Abdul Rani
Raja Affendi Raja Ali
Yeong Yeh Lee
Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
Intestinal Research
Irritable bowel syndrome
Inflammatory bowel disease
Gut-brain axis
IBS-IBD overlap syndrome
title Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
title_full Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
title_fullStr Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
title_full_unstemmed Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
title_short Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
title_sort irritable bowel syndrome and inflammatory bowel disease overlap syndrome pieces of the puzzle are falling into place
topic Irritable bowel syndrome
Inflammatory bowel disease
Gut-brain axis
IBS-IBD overlap syndrome
url http://www.irjournal.org/upload/pdf/ir-14-297.pdf
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