Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place
Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiolo...
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Format: | Article |
Language: | English |
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Korean Association for the Study of Intestinal Diseases
2016-10-01
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Series: | Intestinal Research |
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Online Access: | http://www.irjournal.org/upload/pdf/ir-14-297.pdf |
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author | Rafiz Abdul Rani Raja Affendi Raja Ali Yeong Yeh Lee |
author_facet | Rafiz Abdul Rani Raja Affendi Raja Ali Yeong Yeh Lee |
author_sort | Rafiz Abdul Rani |
collection | DOAJ |
description | Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm. |
first_indexed | 2024-12-13T15:29:03Z |
format | Article |
id | doaj.art-6fc1cc53440a40a39ba877324da4cad1 |
institution | Directory Open Access Journal |
issn | 1598-9100 2288-1956 |
language | English |
last_indexed | 2024-12-13T15:29:03Z |
publishDate | 2016-10-01 |
publisher | Korean Association for the Study of Intestinal Diseases |
record_format | Article |
series | Intestinal Research |
spelling | doaj.art-6fc1cc53440a40a39ba877324da4cad12022-12-21T23:40:15ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562016-10-0114429730410.5217/ir.2016.14.4.297165Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into placeRafiz Abdul Rani0Raja Affendi Raja Ali1Yeong Yeh Lee2Gastroenterology Unit, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia.Gastroenterology Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm.http://www.irjournal.org/upload/pdf/ir-14-297.pdfIrritable bowel syndromeInflammatory bowel diseaseGut-brain axisIBS-IBD overlap syndrome |
spellingShingle | Rafiz Abdul Rani Raja Affendi Raja Ali Yeong Yeh Lee Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place Intestinal Research Irritable bowel syndrome Inflammatory bowel disease Gut-brain axis IBS-IBD overlap syndrome |
title | Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place |
title_full | Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place |
title_fullStr | Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place |
title_full_unstemmed | Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place |
title_short | Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: pieces of the puzzle are falling into place |
title_sort | irritable bowel syndrome and inflammatory bowel disease overlap syndrome pieces of the puzzle are falling into place |
topic | Irritable bowel syndrome Inflammatory bowel disease Gut-brain axis IBS-IBD overlap syndrome |
url | http://www.irjournal.org/upload/pdf/ir-14-297.pdf |
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