Thrombosis of the Abdominal Veins in Childhood

Abdominal venous thrombosis is a rare form of venous thromboembolic disease in children. While mortality rates are low, a significant proportion of affected children may suffer long-term morbidity. Additionally, given the infrequency of these thrombi, there is lack of stringent research data and evi...

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Main Authors: Riten Kumar, Bryce A. Kerlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2017.00188/full
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author Riten Kumar
Riten Kumar
Bryce A. Kerlin
Bryce A. Kerlin
Bryce A. Kerlin
author_facet Riten Kumar
Riten Kumar
Bryce A. Kerlin
Bryce A. Kerlin
Bryce A. Kerlin
author_sort Riten Kumar
collection DOAJ
description Abdominal venous thrombosis is a rare form of venous thromboembolic disease in children. While mortality rates are low, a significant proportion of affected children may suffer long-term morbidity. Additionally, given the infrequency of these thrombi, there is lack of stringent research data and evidence-based treatment guidelines. Nonetheless, pediatric hematologists and other subspecialists are likely to encounter these problems in practice. This review is therefore intended to provide a useful guide on the clinical diagnosis and management of children with these rare forms of venous thromboembolic disease. Herein, we will thus appraise the current knowledge regarding major forms of abdominal venous thrombosis in children. The discussion will focus on the epidemiology, presentation, diagnosis, management, and outcomes of (1) inferior vena cava, (2) portal, (3) mesenteric, (4) hepatic, and (5) renal vein thrombosis.
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spelling doaj.art-6fc2b5301373495bae40f72f8c05cbb92022-12-21T23:29:45ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602017-09-01510.3389/fped.2017.00188245615Thrombosis of the Abdominal Veins in ChildhoodRiten Kumar0Riten Kumar1Bryce A. Kerlin2Bryce A. Kerlin3Bryce A. Kerlin4Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, United StatesDivision of Pediatric Hematology/Oncology/BMT, Nationwide Children’s Hospital, Columbus, OH, United StatesDepartment of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, United StatesDivision of Pediatric Hematology/Oncology/BMT, Nationwide Children’s Hospital, Columbus, OH, United StatesCenter for Clinical and Translational Research, The Research Institute at Nationwide Children’s Hospital, Columbus, OH, United StatesAbdominal venous thrombosis is a rare form of venous thromboembolic disease in children. While mortality rates are low, a significant proportion of affected children may suffer long-term morbidity. Additionally, given the infrequency of these thrombi, there is lack of stringent research data and evidence-based treatment guidelines. Nonetheless, pediatric hematologists and other subspecialists are likely to encounter these problems in practice. This review is therefore intended to provide a useful guide on the clinical diagnosis and management of children with these rare forms of venous thromboembolic disease. Herein, we will thus appraise the current knowledge regarding major forms of abdominal venous thrombosis in children. The discussion will focus on the epidemiology, presentation, diagnosis, management, and outcomes of (1) inferior vena cava, (2) portal, (3) mesenteric, (4) hepatic, and (5) renal vein thrombosis.http://journal.frontiersin.org/article/10.3389/fped.2017.00188/fullthrombosisinferior vena cavaportal veinmesenteric veinBudd–Chiarirenal vein
spellingShingle Riten Kumar
Riten Kumar
Bryce A. Kerlin
Bryce A. Kerlin
Bryce A. Kerlin
Thrombosis of the Abdominal Veins in Childhood
Frontiers in Pediatrics
thrombosis
inferior vena cava
portal vein
mesenteric vein
Budd–Chiari
renal vein
title Thrombosis of the Abdominal Veins in Childhood
title_full Thrombosis of the Abdominal Veins in Childhood
title_fullStr Thrombosis of the Abdominal Veins in Childhood
title_full_unstemmed Thrombosis of the Abdominal Veins in Childhood
title_short Thrombosis of the Abdominal Veins in Childhood
title_sort thrombosis of the abdominal veins in childhood
topic thrombosis
inferior vena cava
portal vein
mesenteric vein
Budd–Chiari
renal vein
url http://journal.frontiersin.org/article/10.3389/fped.2017.00188/full
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AT bryceakerlin thrombosisoftheabdominalveinsinchildhood