Advanced bioactive nanomaterials for biomedical applications

Abstract Bioactive materials are a kind of materials with unique bioactivities, which can change the cellular behaviors and elicit biological responses from living tissues. Bioactive materials came into the spotlight in the late 1960s when the researchers found that the materials such as bioglass co...

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Main Authors: Yu Zhao, Zhanzhan Zhang, Zheng Pan, Yang Liu
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Exploration
Subjects:
Online Access:https://doi.org/10.1002/EXP.20210089
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author Yu Zhao
Zhanzhan Zhang
Zheng Pan
Yang Liu
author_facet Yu Zhao
Zhanzhan Zhang
Zheng Pan
Yang Liu
author_sort Yu Zhao
collection DOAJ
description Abstract Bioactive materials are a kind of materials with unique bioactivities, which can change the cellular behaviors and elicit biological responses from living tissues. Bioactive materials came into the spotlight in the late 1960s when the researchers found that the materials such as bioglass could react with surrounding bone tissue for bone regeneration. In the following decades, advances in nanotechnology brought the new development opportunities to bioactive nanomaterials. Bioactive nanomaterials are not a simple miniaturization of macroscopic materials. They exhibit unique bioactivities due to their nanoscale size effect, high specific surface area, and precise nanostructure, which can significantly influence the interactions with biological systems. Nowadays, bioactive nanomaterials have represented an important and exciting area of research. Current and future applications ensure that bioactive nanomaterials have a high academic and clinical importance. This review summaries the recent advances in the field of bioactive nanomaterials, and evaluate the influence factors of bioactivities. Then, a range of bioactive nanomaterials and their potential biomedical applications are discussed. Furthermore, the limitations, challenges, and future opportunities of bioactive nanomaterials are also discussed.
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spelling doaj.art-6fc611b071734f459f7af7d47813baf52023-05-06T11:00:46ZengWileyExploration2766-85092766-20982021-12-0113n/an/a10.1002/EXP.20210089Advanced bioactive nanomaterials for biomedical applicationsYu Zhao0Zhanzhan Zhang1Zheng Pan2Yang Liu3Key Laboratory of Functional Polymer Materials of Ministry of Education State Key Laboratory of Medicinal Chemical Biology Frontiers Science Center for New Organic Matter College of Chemistry Nankai University Tianjin P. R. ChinaKey Laboratory of Functional Polymer Materials of Ministry of Education State Key Laboratory of Medicinal Chemical Biology Frontiers Science Center for New Organic Matter College of Chemistry Nankai University Tianjin P. R. ChinaKey Laboratory of Functional Polymer Materials of Ministry of Education State Key Laboratory of Medicinal Chemical Biology Frontiers Science Center for New Organic Matter College of Chemistry Nankai University Tianjin P. R. ChinaKey Laboratory of Functional Polymer Materials of Ministry of Education State Key Laboratory of Medicinal Chemical Biology Frontiers Science Center for New Organic Matter College of Chemistry Nankai University Tianjin P. R. ChinaAbstract Bioactive materials are a kind of materials with unique bioactivities, which can change the cellular behaviors and elicit biological responses from living tissues. Bioactive materials came into the spotlight in the late 1960s when the researchers found that the materials such as bioglass could react with surrounding bone tissue for bone regeneration. In the following decades, advances in nanotechnology brought the new development opportunities to bioactive nanomaterials. Bioactive nanomaterials are not a simple miniaturization of macroscopic materials. They exhibit unique bioactivities due to their nanoscale size effect, high specific surface area, and precise nanostructure, which can significantly influence the interactions with biological systems. Nowadays, bioactive nanomaterials have represented an important and exciting area of research. Current and future applications ensure that bioactive nanomaterials have a high academic and clinical importance. This review summaries the recent advances in the field of bioactive nanomaterials, and evaluate the influence factors of bioactivities. Then, a range of bioactive nanomaterials and their potential biomedical applications are discussed. Furthermore, the limitations, challenges, and future opportunities of bioactive nanomaterials are also discussed.https://doi.org/10.1002/EXP.20210089bioactive nanomaterialsbiomedical applicationsnanotopographyphysical structuresurface properties
spellingShingle Yu Zhao
Zhanzhan Zhang
Zheng Pan
Yang Liu
Advanced bioactive nanomaterials for biomedical applications
Exploration
bioactive nanomaterials
biomedical applications
nanotopography
physical structure
surface properties
title Advanced bioactive nanomaterials for biomedical applications
title_full Advanced bioactive nanomaterials for biomedical applications
title_fullStr Advanced bioactive nanomaterials for biomedical applications
title_full_unstemmed Advanced bioactive nanomaterials for biomedical applications
title_short Advanced bioactive nanomaterials for biomedical applications
title_sort advanced bioactive nanomaterials for biomedical applications
topic bioactive nanomaterials
biomedical applications
nanotopography
physical structure
surface properties
url https://doi.org/10.1002/EXP.20210089
work_keys_str_mv AT yuzhao advancedbioactivenanomaterialsforbiomedicalapplications
AT zhanzhanzhang advancedbioactivenanomaterialsforbiomedicalapplications
AT zhengpan advancedbioactivenanomaterialsforbiomedicalapplications
AT yangliu advancedbioactivenanomaterialsforbiomedicalapplications