Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan
The plants of genus Cymbopogon are well known for their use in traditional medicine and for their high content of essential oils that are widely used as flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils isolated from the dried stems and inflorescence of cultivated...
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| Format: | Article |
| Language: | English |
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University of Belgrade, University of Novi Sad
2017-01-01
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| Series: | Archives of Biological Sciences |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600113P.pdf |
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| author | Pavlović Ivan Omar Eihab Drobac Milica Radenković Mirjana Branković Suzana Kovačević Nada |
| author_facet | Pavlović Ivan Omar Eihab Drobac Milica Radenković Mirjana Branković Suzana Kovačević Nada |
| author_sort | Pavlović Ivan |
| collection | DOAJ |
| description | The plants of genus Cymbopogon are well known for their use in traditional
medicine and for their high content of essential oils that are widely used as
flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils
isolated from the dried stems and inflorescence of cultivated Cymbopogon
schoenanthus (L.) Spreng. (Poaceae) collected from Khartoum state (Sudan) in
two periods were studied. The results of chemical analysis of C. schoenanthus
revealed that this plant is rich in essential oil which is a valuable source
of the commercially important monoterpene, piperitone (47.7-71.5%). Other
abundant constituents of the oils were intermedeol (6.1-17.3%), δ-2-carene
(4.5-10.0%) and elemol (2.7-9.0%). The essential oil from the inflorescence
was tested for spasmolytic activity using three different experimental
models: against spontaneous contractions, contractions induced with
acetylcholine and contractions induced with potassium chloride. The oil
exhibited strong, significant and dose-dependent spasmolytic activity,
indicating the possibility for further investigations of this essential oil
for its medicinal purposes or application in food industry. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no.173021 and Grant no. III41018] |
| first_indexed | 2024-12-10T16:55:28Z |
| format | Article |
| id | doaj.art-6fc7c81ce75d4fcaa1d54a5b647c631a |
| institution | Directory Open Access Journal |
| issn | 0354-4664 1821-4339 |
| language | English |
| last_indexed | 2024-12-10T16:55:28Z |
| publishDate | 2017-01-01 |
| publisher | University of Belgrade, University of Novi Sad |
| record_format | Article |
| series | Archives of Biological Sciences |
| spelling | doaj.art-6fc7c81ce75d4fcaa1d54a5b647c631a2022-12-22T01:40:45ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392017-01-0169340941510.2298/ABS160506113P0354-46641600113PChemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from SudanPavlović Ivan0Omar Eihab1Drobac Milica2Radenković Mirjana3Branković Suzana4Kovačević Nada5Faculty of Pharmacy, Department of Pharmacognosy, BelgradeOmdurman Islamic University, Faculty of Pharmacy, Department of Pharmacognosy, Omdurman, SudanFaculty of Pharmacy, Department of Pharmacognosy, BelgradeFaculty of Medicine, Department of Physiology, NišFaculty of Medicine, Department of Physiology, NišFaculty of Pharmacy, Department of Pharmacognosy, BelgradeThe plants of genus Cymbopogon are well known for their use in traditional medicine and for their high content of essential oils that are widely used as flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils isolated from the dried stems and inflorescence of cultivated Cymbopogon schoenanthus (L.) Spreng. (Poaceae) collected from Khartoum state (Sudan) in two periods were studied. The results of chemical analysis of C. schoenanthus revealed that this plant is rich in essential oil which is a valuable source of the commercially important monoterpene, piperitone (47.7-71.5%). Other abundant constituents of the oils were intermedeol (6.1-17.3%), δ-2-carene (4.5-10.0%) and elemol (2.7-9.0%). The essential oil from the inflorescence was tested for spasmolytic activity using three different experimental models: against spontaneous contractions, contractions induced with acetylcholine and contractions induced with potassium chloride. The oil exhibited strong, significant and dose-dependent spasmolytic activity, indicating the possibility for further investigations of this essential oil for its medicinal purposes or application in food industry. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no.173021 and Grant no. III41018]http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600113P.pdfCymbopogon schoenanthusessential oil compositionpiperitonespasmolytic activity |
| spellingShingle | Pavlović Ivan Omar Eihab Drobac Milica Radenković Mirjana Branković Suzana Kovačević Nada Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan Archives of Biological Sciences Cymbopogon schoenanthus essential oil composition piperitone spasmolytic activity |
| title | Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan |
| title_full | Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan |
| title_fullStr | Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan |
| title_full_unstemmed | Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan |
| title_short | Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan |
| title_sort | chemical composition and spasmolytic activity of cymbopogon schoenanthus l spreng poaceae essential oil from sudan |
| topic | Cymbopogon schoenanthus essential oil composition piperitone spasmolytic activity |
| url | http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600113P.pdf |
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