Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research
The enzymes called ribosome‐inactivating proteins (RIPs) that are able to depurinate nucleic acids and arrest vital cellular functions, including protein synthesis, are still a frontline research field, mostly because of their promising medical applications. The contributions of Stirpe to the dev...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/22/2/206 |
| _version_ | 1828293759358468096 |
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| author | Andrea Bolognesi Massimo Bortolotti Maria Giulia Battelli Letizia Polito |
| author_facet | Andrea Bolognesi Massimo Bortolotti Maria Giulia Battelli Letizia Polito |
| author_sort | Andrea Bolognesi |
| collection | DOAJ |
| description | The enzymes called ribosome‐inactivating proteins (RIPs) that are able to depurinate nucleic acids and arrest vital cellular functions, including protein synthesis, are still a frontline research field, mostly because of their promising medical applications. The contributions of Stirpe to the development of these studies has been one of the most relevant. After a short biographical introduction, an overview is offered of the main results obtained by his investigations during last 55 years on his main research lines: hyperuricaemia, xanthine oxidoreductase and RIPs. |
| first_indexed | 2024-04-13T11:26:25Z |
| format | Article |
| id | doaj.art-6fcbddf1133c4d178c331d15e08f385f |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T11:26:25Z |
| publishDate | 2017-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6fcbddf1133c4d178c331d15e08f385f2022-12-22T02:48:41ZengMDPI AGMolecules1420-30492017-01-0122220610.3390/molecules22020206molecules22020206Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline ResearchAndrea Bolognesi0Massimo Bortolotti1Maria Giulia Battelli2Letizia Polito3Department of Experimental, Diagnostic and Specialty Medicine‐DIMES, Alma Mater Studiorum, University of Bologna, Via San Giacomo 14, 40126 Bologna, ItalyDepartment of Experimental, Diagnostic and Specialty Medicine‐DIMES, Alma Mater Studiorum, University of Bologna, Via San Giacomo 14, 40126 Bologna, ItalyDepartment of Experimental, Diagnostic and Specialty Medicine‐DIMES, Alma Mater Studiorum, University of Bologna, Via San Giacomo 14, 40126 Bologna, ItalyDepartment of Experimental, Diagnostic and Specialty Medicine‐DIMES, Alma Mater Studiorum, University of Bologna, Via San Giacomo 14, 40126 Bologna, ItalyThe enzymes called ribosome‐inactivating proteins (RIPs) that are able to depurinate nucleic acids and arrest vital cellular functions, including protein synthesis, are still a frontline research field, mostly because of their promising medical applications. The contributions of Stirpe to the development of these studies has been one of the most relevant. After a short biographical introduction, an overview is offered of the main results obtained by his investigations during last 55 years on his main research lines: hyperuricaemia, xanthine oxidoreductase and RIPs.http://www.mdpi.com/1420-3049/22/2/206gout hyperuricaemia immunotoxins ribosome‐inactivating proteins ricin toxic lectins xanthine oxidoreductase |
| spellingShingle | Andrea Bolognesi Massimo Bortolotti Maria Giulia Battelli Letizia Polito Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research Molecules gout hyperuricaemia immunotoxins ribosome‐inactivating proteins ricin toxic lectins xanthine oxidoreductase |
| title | Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research |
| title_full | Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research |
| title_fullStr | Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research |
| title_full_unstemmed | Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research |
| title_short | Hyperuricaemia, Xanthine Oxidoreductase and Ribosome‐Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research |
| title_sort | hyperuricaemia xanthine oxidoreductase and ribosome inactivating proteins from plants the contributions of fiorenzo stirpe to frontline research |
| topic | gout hyperuricaemia immunotoxins ribosome‐inactivating proteins ricin toxic lectins xanthine oxidoreductase |
| url | http://www.mdpi.com/1420-3049/22/2/206 |
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