The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver

The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver

Background: A growing body of data indicates that the physiology of the liver is sex-hormone dependent, with some types of liver failure occurring more frequently in males, and some in females. In males, in physiological conditions, testosterone acts via androgen receptors (AR) to increase insulin r...

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Bibliographic Details
Main Authors: Paulina Kur, Agnieszka Kolasa-Wołosiuk, Marta Grabowska, Andrzej Kram, Maciej Tarnowski, Irena Baranowska-Bosiacka, Sylwia Rzeszotek, Małgorzata Piasecka, Barbara Wiszniewska
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
glycogen storage
GLUT-2
AR
IR
finasteride
DHT deficiency
Online Access:https://www.mdpi.com/1422-0067/22/3/1242

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