Three-dimensional analysis of perineural invasion in extrahepatic cholangiocarcinoma using tissue clearing

Three-dimensional analysis of perineural invasion in extrahepatic cholangiocarcinoma using tissue clearing

Perineural invasion (PNI) is a characteristic invasion pattern of distal cholangiocarcinoma (DCC). Conventional histopathologic examination is a challenging approach to analyze the spatial relationship between cancer and neural tissue in full-thickness bile duct specimens. Therefore, we used a tissu...

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Bibliographic Details
Main Authors: Hirokazu Ogasawara, Tadashi Yoshizawa, Kiyoko Oshima, Kenta Ogasawara, Shunsuke Kubota, Shintaro Goto, Satoko Morohashi, Taiichi Wakiya, Norihisa Kimura, Keinosuke Ishido, Hiroshi Kijima, Kenichi Hakamada
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Pathology and Oncology Research
Subjects:
tissue clearing
three-dimensional
perineural invasion
cholangiocarcinoma
iDISCO
Online Access:https://www.por-journal.com/articles/10.3389/pore.2023.1611284/full

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https://www.por-journal.com/articles/10.3389/pore.2023.1611284/full

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