Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
Aim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Mat...
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Format: | Article |
Language: | Russian |
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IP Morozov P.V.
2009-09-01
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Series: | Системные гипертензии |
Subjects: | |
Online Access: | https://syst-hypertension.ru/2075-082X/article/view/33076 |
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author | G V Ryabykina T A Shishova D N Laptev V B Mychka L N Lyutikova E Sh Kozhemyakina E V Shchedrina A V Sobolev I E Chazova |
author_facet | G V Ryabykina T A Shishova D N Laptev V B Mychka L N Lyutikova E Sh Kozhemyakina E V Shchedrina A V Sobolev I E Chazova |
author_sort | G V Ryabykina |
collection | DOAJ |
description | Aim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation
(AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker,
metformin and their combination.
Materials: 51 patients with МС and AH were enrolled in the study. The patients were randomization on 3 groups:
the monotherapy of nebivolol (N) 5 mg/days (n=18), the monotherapy of metformin (M) 1700 mg/days (n=15) and nebivolol+metformin
combination therapy (N+M) (n=18). The estimated variables included of BP, HRV, AWRV and QTc before and after 24 weeks of
the treatment.
Results: after 24 weeks of the N treatment QTc interval change from 44823 ms to 43317ms (p0.05). Treatment of M changes AWRV from 872234 ms to 761195 (p>0.05), QTc from
44825 ms to 43427 ms (p |
first_indexed | 2024-12-19T04:52:51Z |
format | Article |
id | doaj.art-6fd54f8956874269931afad6c4ee8fbf |
institution | Directory Open Access Journal |
issn | 2075-082X 2542-2189 |
language | Russian |
last_indexed | 2024-12-19T04:52:51Z |
publishDate | 2009-09-01 |
publisher | IP Morozov P.V. |
record_format | Article |
series | Системные гипертензии |
spelling | doaj.art-6fd54f8956874269931afad6c4ee8fbf2022-12-21T20:35:19ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892009-09-0163385629817Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.G V RyabykinaT A ShishovaD N LaptevV B MychkaL N LyutikovaE Sh KozhemyakinaE V ShchedrinaA V SobolevI E ChazovaAim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Materials: 51 patients with МС and AH were enrolled in the study. The patients were randomization on 3 groups: the monotherapy of nebivolol (N) 5 mg/days (n=18), the monotherapy of metformin (M) 1700 mg/days (n=15) and nebivolol+metformin combination therapy (N+M) (n=18). The estimated variables included of BP, HRV, AWRV and QTc before and after 24 weeks of the treatment. Results: after 24 weeks of the N treatment QTc interval change from 44823 ms to 43317ms (p0.05). Treatment of M changes AWRV from 872234 ms to 761195 (p>0.05), QTc from 44825 ms to 43427 ms (phttps://syst-hypertension.ru/2075-082X/article/view/33076qtcarterial hypertensionhrvawrvqtc |
spellingShingle | G V Ryabykina T A Shishova D N Laptev V B Mychka L N Lyutikova E Sh Kozhemyakina E V Shchedrina A V Sobolev I E Chazova Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. Системные гипертензии qtc arterial hypertension hrv awrv qtc |
title | Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. |
title_full | Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. |
title_fullStr | Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. |
title_full_unstemmed | Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. |
title_short | Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy. |
title_sort | dynamics of blood pressure heart rate variability and qtc in patients with metabolic syndrome on the selective betablockerand biguanide therapy |
topic | qtc arterial hypertension hrv awrv qtc |
url | https://syst-hypertension.ru/2075-082X/article/view/33076 |
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