Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.

Aim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Mat...

Full description

Bibliographic Details
Main Authors: G V Ryabykina, T A Shishova, D N Laptev, V B Mychka, L N Lyutikova, E Sh Kozhemyakina, E V Shchedrina, A V Sobolev, I E Chazova
Format: Article
Language:Russian
Published: IP Morozov P.V. 2009-09-01
Series:Системные гипертензии
Subjects:
Online Access:https://syst-hypertension.ru/2075-082X/article/view/33076
_version_ 1818843122009899008
author G V Ryabykina
T A Shishova
D N Laptev
V B Mychka
L N Lyutikova
E Sh Kozhemyakina
E V Shchedrina
A V Sobolev
I E Chazova
author_facet G V Ryabykina
T A Shishova
D N Laptev
V B Mychka
L N Lyutikova
E Sh Kozhemyakina
E V Shchedrina
A V Sobolev
I E Chazova
author_sort G V Ryabykina
collection DOAJ
description Aim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Materials: 51 patients with МС and AH were enrolled in the study. The patients were randomization on 3 groups: the monotherapy of nebivolol (N) 5 mg/days (n=18), the monotherapy of metformin (M) 1700 mg/days (n=15) and nebivolol+metformin combination therapy (N+M) (n=18). The estimated variables included of BP, HRV, AWRV and QTc before and after 24 weeks of the treatment. Results: after 24 weeks of the N treatment QTc interval change from 44823 ms to 43317ms (p0.05). Treatment of M changes AWRV from 872234 ms to 761195 (p>0.05), QTc from 44825 ms to 43427 ms (p
first_indexed 2024-12-19T04:52:51Z
format Article
id doaj.art-6fd54f8956874269931afad6c4ee8fbf
institution Directory Open Access Journal
issn 2075-082X
2542-2189
language Russian
last_indexed 2024-12-19T04:52:51Z
publishDate 2009-09-01
publisher IP Morozov P.V.
record_format Article
series Системные гипертензии
spelling doaj.art-6fd54f8956874269931afad6c4ee8fbf2022-12-21T20:35:19ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892009-09-0163385629817Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.G V RyabykinaT A ShishovaD N LaptevV B MychkaL N LyutikovaE Sh KozhemyakinaE V ShchedrinaA V SobolevI E ChazovaAim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Materials: 51 patients with МС and AH were enrolled in the study. The patients were randomization on 3 groups: the monotherapy of nebivolol (N) 5 mg/days (n=18), the monotherapy of metformin (M) 1700 mg/days (n=15) and nebivolol+metformin combination therapy (N+M) (n=18). The estimated variables included of BP, HRV, AWRV and QTc before and after 24 weeks of the treatment. Results: after 24 weeks of the N treatment QTc interval change from 44823 ms to 43317ms (p0.05). Treatment of M changes AWRV from 872234 ms to 761195 (p>0.05), QTc from 44825 ms to 43427 ms (phttps://syst-hypertension.ru/2075-082X/article/view/33076qtcarterial hypertensionhrvawrvqtc
spellingShingle G V Ryabykina
T A Shishova
D N Laptev
V B Mychka
L N Lyutikova
E Sh Kozhemyakina
E V Shchedrina
A V Sobolev
I E Chazova
Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
Системные гипертензии
qtc
arterial hypertension
hrv
awrv
qtc
title Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
title_full Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
title_fullStr Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
title_full_unstemmed Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
title_short Dynamics of blood pressure, heart rate variability and QTc in patients with metabolic syndrome on the selective betablockerand biguanide therapy.
title_sort dynamics of blood pressure heart rate variability and qtc in patients with metabolic syndrome on the selective betablockerand biguanide therapy
topic qtc
arterial hypertension
hrv
awrv
qtc
url https://syst-hypertension.ru/2075-082X/article/view/33076
work_keys_str_mv AT gvryabykina dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT tashishova dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT dnlaptev dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT vbmychka dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT lnlyutikova dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT eshkozhemyakina dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT evshchedrina dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT avsobolev dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy
AT iechazova dynamicsofbloodpressureheartratevariabilityandqtcinpatientswithmetabolicsyndromeontheselectivebetablockerandbiguanidetherapy