Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?

Pulmonary complications post hematopoietic stem cell transplant (HSCT) are associated with poor outcomes and require extensive management depending on the etiology. They usually present in the form of bronchiolitis obliterans syndrome, interstitial pneumonitis, or drug toxicity that can lead to fibr...

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Main Authors: Walid Alam, Rayan Mohamad, Maysoun Koubaissi, Salwa A Koubaissi
Format: Article
Language:English
Published: SAGE Publishing 2022-05-01
Series:Clinical Medicine Insights: Case Reports
Online Access:https://doi.org/10.1177/11795476221097317
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author Walid Alam
Rayan Mohamad
Maysoun Koubaissi
Salwa A Koubaissi
author_facet Walid Alam
Rayan Mohamad
Maysoun Koubaissi
Salwa A Koubaissi
author_sort Walid Alam
collection DOAJ
description Pulmonary complications post hematopoietic stem cell transplant (HSCT) are associated with poor outcomes and require extensive management depending on the etiology. They usually present in the form of bronchiolitis obliterans syndrome, interstitial pneumonitis, or drug toxicity that can lead to fibrosis. Scant data exists regarding diffuse cystic lung disease following HSCT, and the existing literature only mentions mild cystic changes. We present the case of a 25-year-old man with stage IVB Hodgkin’s lymphoma post allogeneic HSCT, who developed progressive traction bronchiectasis, with the appearance of extensive pulmonary cysts that followed significant fibrotic changes and discuss the possible etiologies behind it.
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spelling doaj.art-6fd64119f78b4b38a6f1d91146b4509f2022-12-22T03:25:08ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762022-05-011510.1177/11795476221097317Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?Walid Alam0Rayan Mohamad1Maysoun Koubaissi2Salwa A Koubaissi3Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, LebanonPulmonary and Critical Care Division, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, Lebanese University, Beirut, LebanonPulmonary and Critical Care Division, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonPulmonary complications post hematopoietic stem cell transplant (HSCT) are associated with poor outcomes and require extensive management depending on the etiology. They usually present in the form of bronchiolitis obliterans syndrome, interstitial pneumonitis, or drug toxicity that can lead to fibrosis. Scant data exists regarding diffuse cystic lung disease following HSCT, and the existing literature only mentions mild cystic changes. We present the case of a 25-year-old man with stage IVB Hodgkin’s lymphoma post allogeneic HSCT, who developed progressive traction bronchiectasis, with the appearance of extensive pulmonary cysts that followed significant fibrotic changes and discuss the possible etiologies behind it.https://doi.org/10.1177/11795476221097317
spellingShingle Walid Alam
Rayan Mohamad
Maysoun Koubaissi
Salwa A Koubaissi
Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
Clinical Medicine Insights: Case Reports
title Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
title_full Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
title_fullStr Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
title_full_unstemmed Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
title_short Fibrotic Cystic Lung Disease Post Hematopoietic Stem Cell Transplant: Who is the Culprit?
title_sort fibrotic cystic lung disease post hematopoietic stem cell transplant who is the culprit
url https://doi.org/10.1177/11795476221097317
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AT salwaakoubaissi fibroticcysticlungdiseaseposthematopoieticstemcelltransplantwhoistheculprit