Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose
Most genetic studies of glucose levels have been done on fasting samples, which can be difficult to obtain. Here, the authors identify 156 genetic loci controlling the physiological variation of glucose levels in healthy non-fasting individuals, demonstrating that the results non-fasting samples can...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36013-1 |
| _version_ | 1811175816842706944 |
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| author | Zhen Qiao Julia Sidorenko Joana A. Revez Angli Xue Xueling Lu Katri Pärna Harold Snieder Lifelines Cohort Study Peter M. Visscher Naomi R. Wray Loic Yengo |
| author_facet | Zhen Qiao Julia Sidorenko Joana A. Revez Angli Xue Xueling Lu Katri Pärna Harold Snieder Lifelines Cohort Study Peter M. Visscher Naomi R. Wray Loic Yengo |
| author_sort | Zhen Qiao |
| collection | DOAJ |
| description | Most genetic studies of glucose levels have been done on fasting samples, which can be difficult to obtain. Here, the authors identify 156 genetic loci controlling the physiological variation of glucose levels in healthy non-fasting individuals, demonstrating that the results non-fasting samples can be used to predict fasting glucose levels. |
| first_indexed | 2024-04-10T19:42:02Z |
| format | Article |
| id | doaj.art-6fde8113956e402caba8686de06ed2d1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T19:42:02Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-6fde8113956e402caba8686de06ed2d12023-01-29T12:16:15ZengNature PortfolioNature Communications2041-17232023-01-0114111110.1038/s41467-023-36013-1Estimation and implications of the genetic architecture of fasting and non-fasting blood glucoseZhen Qiao0Julia Sidorenko1Joana A. Revez2Angli Xue3Xueling Lu4Katri Pärna5Harold Snieder6Lifelines Cohort StudyPeter M. Visscher7Naomi R. Wray8Loic Yengo9Garvan Institute of Medical ResearchInstitute for Molecular Bioscience, The University of QueenslandInstitute for Molecular Bioscience, The University of QueenslandGarvan Institute of Medical ResearchDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Epidemiology, University of Groningen, University Medical Center GroningenDepartment of Epidemiology, University of Groningen, University Medical Center GroningenInstitute for Molecular Bioscience, The University of QueenslandInstitute for Molecular Bioscience, The University of QueenslandInstitute for Molecular Bioscience, The University of QueenslandMost genetic studies of glucose levels have been done on fasting samples, which can be difficult to obtain. Here, the authors identify 156 genetic loci controlling the physiological variation of glucose levels in healthy non-fasting individuals, demonstrating that the results non-fasting samples can be used to predict fasting glucose levels.https://doi.org/10.1038/s41467-023-36013-1 |
| spellingShingle | Zhen Qiao Julia Sidorenko Joana A. Revez Angli Xue Xueling Lu Katri Pärna Harold Snieder Lifelines Cohort Study Peter M. Visscher Naomi R. Wray Loic Yengo Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose Nature Communications |
| title | Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose |
| title_full | Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose |
| title_fullStr | Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose |
| title_full_unstemmed | Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose |
| title_short | Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose |
| title_sort | estimation and implications of the genetic architecture of fasting and non fasting blood glucose |
| url | https://doi.org/10.1038/s41467-023-36013-1 |
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