Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome
Chronic nonbacterial prostatitis/chronic pelvic pain syndrome is unsatisfactorily defined and insufficiently studied illness. Also, the treatment success is questionable and therefore, this illness is a therapeutical problem for urologists - which medications are the best choice in treating this unc...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2007-08-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3053 |
| _version_ | 1797260826646675456 |
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| author | Benjamin Kulovac Damir Aganović Alden Prcić Osman Hadžiosmanović |
| author_facet | Benjamin Kulovac Damir Aganović Alden Prcić Osman Hadžiosmanović |
| author_sort | Benjamin Kulovac |
| collection | DOAJ |
| description | Chronic nonbacterial prostatitis/chronic pelvic pain syndrome is unsatisfactorily defined and insufficiently studied illness. Also, the treatment success is questionable and therefore, this illness is a therapeutical problem for urologists - which medications are the best choice in treating this uncomfortable condition?
This paper presents results of prospective, open, analytical, comparative study that was performed on 90 patients with diagnosed chronic nonbacterial prostatitis/chronic pelvic pain syndrome. Patients were divided into three groups and were treated with two medications ciprofloxacin (C), doxazosin (D) and combination of ciprofloxacin + doxazosin (C+D). The effects were measured using symptom questionnaire for prostate illnesses of the National Institute for Health - USA (NIH-CPSI). During the basic evaluation, sum ranging from 0 to 43 was calculated for each patient. This number is called total sum NIH-CPSI (National Institutes of Health Chronic Prostatitis Symptom Index) of the questionnaire, which generates the questions from 1 to 9.
The most significant change occurred in C+D group where the total sum changed from 18-38 in the beginning to 5-31 at the end of the treatment (55,1% (p<0,001)). Significant changes were also found in D group where the change was 46, 4% (p<0,001). At the end of the treatment no significant change was registered in C group (p<0,005): p<0,001 – significance threshold. Combination of ciprofloxacin + doxazosin proved to be the best choice for treatment.
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| first_indexed | 2024-04-24T23:31:30Z |
| format | Article |
| id | doaj.art-6fe2a00a99ca4617a33c9ff13363e946 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:30Z |
| publishDate | 2007-08-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-6fe2a00a99ca4617a33c9ff13363e9462024-03-15T14:38:13ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2007-08-017310.17305/bjbms.2007.3053626Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain SyndromeBenjamin Kulovac0Damir Aganović1Alden Prcić2Osman Hadžiosmanović3Urology Clinic, University of Sarajevo Clinics CentreUrology Clinic, University of Sarajevo Clinics CentreUrology Clinic, University of Sarajevo Clinics CentreUrology Clinic, University of Sarajevo Clinics CentreChronic nonbacterial prostatitis/chronic pelvic pain syndrome is unsatisfactorily defined and insufficiently studied illness. Also, the treatment success is questionable and therefore, this illness is a therapeutical problem for urologists - which medications are the best choice in treating this uncomfortable condition? This paper presents results of prospective, open, analytical, comparative study that was performed on 90 patients with diagnosed chronic nonbacterial prostatitis/chronic pelvic pain syndrome. Patients were divided into three groups and were treated with two medications ciprofloxacin (C), doxazosin (D) and combination of ciprofloxacin + doxazosin (C+D). The effects were measured using symptom questionnaire for prostate illnesses of the National Institute for Health - USA (NIH-CPSI). During the basic evaluation, sum ranging from 0 to 43 was calculated for each patient. This number is called total sum NIH-CPSI (National Institutes of Health Chronic Prostatitis Symptom Index) of the questionnaire, which generates the questions from 1 to 9. The most significant change occurred in C+D group where the total sum changed from 18-38 in the beginning to 5-31 at the end of the treatment (55,1% (p<0,001)). Significant changes were also found in D group where the change was 46, 4% (p<0,001). At the end of the treatment no significant change was registered in C group (p<0,005): p<0,001 – significance threshold. Combination of ciprofloxacin + doxazosin proved to be the best choice for treatment. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3053chronic nonbacterial prostatitis/chronic pelvic pain syndrometherapy |
| spellingShingle | Benjamin Kulovac Damir Aganović Alden Prcić Osman Hadžiosmanović Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome Biomolecules & Biomedicine chronic nonbacterial prostatitis/chronic pelvic pain syndrome therapy |
| title | Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome |
| title_full | Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome |
| title_fullStr | Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome |
| title_full_unstemmed | Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome |
| title_short | Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome |
| title_sort | management of chronic nonbacterial prostatitis chronic pelvic pain syndrome |
| topic | chronic nonbacterial prostatitis/chronic pelvic pain syndrome therapy |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3053 |
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