MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells.

MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells.

MicroRNAs play a pivotal role in cellular maintenance, proliferation, and differentiation. They have also been implicated to play a key role in disease pathogenesis, and more recently, cellular reprogramming. Certain microRNA clusters can enhance or even directly induce reprogramming, while repressi...

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Bibliographic Details
Main Authors: Byeong-Moo Kim, Marc-Christian Thier, Sangnam Oh, Richard Sherwood, Chryssa Kanellopoulou, Frank Edenhofer, Michael Y Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3380844?pdf=render

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