Identifying Susceptibility Loci for Cutaneous Squamous Cell Carcinoma Using a Fast Sequence Kernel Association Test

Identifying Susceptibility Loci for Cutaneous Squamous Cell Carcinoma Using a Fast Sequence Kernel Association Test

Cutaneous squamous cell carcinoma (cSCC) accounts for about 20% of all skin cancers, the most common type of malignancy in the United States. Genome-wide association studies (GWAS) have successfully identified multiple genetic variants associated with the risk of cSCC. Most of these studies were sin...

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Bibliographic Details
Main Authors: Manyan Huang, Chen Lyu, Xin Li, Abrar A. Qureshi, Jiali Han, Ming Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
region-based association test
fast sequence kernel association test
cutaneous squamous cell carcinoma
rare variants
generalized genetic random field
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.657499/full

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