Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions
2,4,6-Trichloro-1,3,5-triazine (TCT) efficiently catalyzed the condensation reactions between 1,2-diamines and various enolizable ketones to afford 1,5-benzodiazepines in good to excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are nota...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2008-09-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/13/9/2313/ |
| _version_ | 1818979743307923456 |
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| author | Ching-Fa Yao Veerababurao Kavala Chun-Chao Wang Chun-Wei Kuo |
| author_facet | Ching-Fa Yao Veerababurao Kavala Chun-Chao Wang Chun-Wei Kuo |
| author_sort | Ching-Fa Yao |
| collection | DOAJ |
| description | 2,4,6-Trichloro-1,3,5-triazine (TCT) efficiently catalyzed the condensation reactions between 1,2-diamines and various enolizable ketones to afford 1,5-benzodiazepines in good to excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method. |
| first_indexed | 2024-12-20T17:04:23Z |
| format | Article |
| id | doaj.art-6feff296b1d44ee3b94a6b666fa5c736 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-20T17:04:23Z |
| publishDate | 2008-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6feff296b1d44ee3b94a6b666fa5c7362022-12-21T19:32:22ZengMDPI AGMolecules1420-30492008-09-011392313232510.3390/molecules13092313Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild ConditionsChing-Fa YaoVeerababurao KavalaChun-Chao WangChun-Wei Kuo2,4,6-Trichloro-1,3,5-triazine (TCT) efficiently catalyzed the condensation reactions between 1,2-diamines and various enolizable ketones to afford 1,5-benzodiazepines in good to excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method.http://www.mdpi.com/1420-3049/13/9/2313/Benzodiazepines246-trichloro-135-triazineenolizable ketoneso-phenylenediamines |
| spellingShingle | Ching-Fa Yao Veerababurao Kavala Chun-Chao Wang Chun-Wei Kuo Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions Molecules Benzodiazepines 2 4 6-trichloro-1 3 5-triazine enolizable ketones o-phenylenediamines |
| title | Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions |
| title_full | Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions |
| title_fullStr | Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions |
| title_full_unstemmed | Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions |
| title_short | Efficient TCT-catalyzed Synthesis of 1,5-Benzodiazepine Derivatives under Mild Conditions |
| title_sort | efficient tct catalyzed synthesis of 1 5 benzodiazepine derivatives under mild conditions |
| topic | Benzodiazepines 2 4 6-trichloro-1 3 5-triazine enolizable ketones o-phenylenediamines |
| url | http://www.mdpi.com/1420-3049/13/9/2313/ |
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