Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives
Abstract Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in realistic scenarios, is of great significance for both basic research and applications. Multiple analytical methods are available for analysis via off-line or on-line measurements. Real-world samples are...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-023-01851-0 |
| _version_ | 1797863678944477184 |
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| author | Xuzhi Zhang Xiangyi Hou Liangyu Ma Yaqi Shi Dahai Zhang Keming Qu |
| author_facet | Xuzhi Zhang Xiangyi Hou Liangyu Ma Yaqi Shi Dahai Zhang Keming Qu |
| author_sort | Xuzhi Zhang |
| collection | DOAJ |
| description | Abstract Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in realistic scenarios, is of great significance for both basic research and applications. Multiple analytical methods are available for analysis via off-line or on-line measurements. Real-world samples are often complex with inorganic and organic components, which complicates the measurements of microbial viability and/or metabolic activity. This article highlights the recent advances achieved in analytical methods including typical applications and specifics regarding their accuracy, cost, efficiency, and user-friendliness. Methodological drawbacks, technique gaps, and future perspectives are also discussed. This review aims to help researchers select suitable methods for gaining insight into antimicrobial activities of targeted ENMs in artificial and natural complex matrices. |
| first_indexed | 2024-04-09T22:39:22Z |
| format | Article |
| id | doaj.art-6ff17e262dcf484f8f14fa93a6eff447 |
| institution | Directory Open Access Journal |
| issn | 1477-3155 |
| language | English |
| last_indexed | 2024-04-09T22:39:22Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj.art-6ff17e262dcf484f8f14fa93a6eff4472023-03-22T12:16:55ZengBMCJournal of Nanobiotechnology1477-31552023-03-0121113010.1186/s12951-023-01851-0Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectivesXuzhi Zhang0Xiangyi Hou1Liangyu Ma2Yaqi Shi3Dahai Zhang4Keming Qu5Laboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery SciencesSchool of Marine Ecology and Environment, Shanghai Ocean UniversityLaboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery SciencesKey Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of ChinaKey Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of ChinaLaboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery SciencesAbstract Assessing the antimicrobial activity of engineered nanomaterials (ENMs), especially in realistic scenarios, is of great significance for both basic research and applications. Multiple analytical methods are available for analysis via off-line or on-line measurements. Real-world samples are often complex with inorganic and organic components, which complicates the measurements of microbial viability and/or metabolic activity. This article highlights the recent advances achieved in analytical methods including typical applications and specifics regarding their accuracy, cost, efficiency, and user-friendliness. Methodological drawbacks, technique gaps, and future perspectives are also discussed. This review aims to help researchers select suitable methods for gaining insight into antimicrobial activities of targeted ENMs in artificial and natural complex matrices.https://doi.org/10.1186/s12951-023-01851-0NanomaterialsAntimicrobial activityComplex matricesAssessmentAnalytical methods |
| spellingShingle | Xuzhi Zhang Xiangyi Hou Liangyu Ma Yaqi Shi Dahai Zhang Keming Qu Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives Journal of Nanobiotechnology Nanomaterials Antimicrobial activity Complex matrices Assessment Analytical methods |
| title | Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives |
| title_full | Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives |
| title_fullStr | Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives |
| title_full_unstemmed | Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives |
| title_short | Analytical methods for assessing antimicrobial activity of nanomaterials in complex media: advances, challenges, and perspectives |
| title_sort | analytical methods for assessing antimicrobial activity of nanomaterials in complex media advances challenges and perspectives |
| topic | Nanomaterials Antimicrobial activity Complex matrices Assessment Analytical methods |
| url | https://doi.org/10.1186/s12951-023-01851-0 |
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