Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system

Abstract Background Machine learning and automation are increasingly used to make the evidence synthesis process faster and more responsive to policymakers’ needs. In systematic reviews of randomized controlled trials (RCTs), risk of bias assessment is a resource-intensive task that typically requir...

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Main Authors: Patricia Sofia Jacobsen Jardim, Christopher James Rose, Heather Melanie Ames, Jose Francisco Meneses Echavez, Stijn Van de Velde, Ashley Elizabeth Muller
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-022-01649-y
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author Patricia Sofia Jacobsen Jardim
Christopher James Rose
Heather Melanie Ames
Jose Francisco Meneses Echavez
Stijn Van de Velde
Ashley Elizabeth Muller
author_facet Patricia Sofia Jacobsen Jardim
Christopher James Rose
Heather Melanie Ames
Jose Francisco Meneses Echavez
Stijn Van de Velde
Ashley Elizabeth Muller
author_sort Patricia Sofia Jacobsen Jardim
collection DOAJ
description Abstract Background Machine learning and automation are increasingly used to make the evidence synthesis process faster and more responsive to policymakers’ needs. In systematic reviews of randomized controlled trials (RCTs), risk of bias assessment is a resource-intensive task that typically requires two trained reviewers. One function of RobotReviewer, an off-the-shelf machine learning system, is an automated risk of bias assessment. Methods We assessed the feasibility of adopting RobotReviewer within a national public health institute using a randomized, real-time, user-centered study. The study included 26 RCTs and six reviewers from two projects examining health and social interventions. We randomized these studies to one of two RobotReviewer platforms. We operationalized feasibility as accuracy, time use, and reviewer acceptability. We measured accuracy by the number of corrections made by human reviewers (either to automated assessments or another human reviewer’s assessments). We explored acceptability through group discussions and individual email responses after presenting the quantitative results. Results Reviewers were equally likely to accept judgment by RobotReviewer as each other’s judgement during the consensus process when measured dichotomously; risk ratio 1.02 (95% CI 0.92 to 1.13; p = 0.33). We were not able to compare time use. The acceptability of the program by researchers was mixed. Less experienced reviewers were generally more positive, and they saw more benefits and were able to use the tool more flexibly. Reviewers positioned human input and human-to-human interaction as superior to even a semi-automation of this process. Conclusion Despite being presented with evidence of RobotReviewer’s equal performance to humans, participating reviewers were not interested in modifying standard procedures to include automation. If further studies confirm equal accuracy and reduced time compared to manual practices, we suggest that the benefits of RobotReviewer may support its future implementation as one of two assessors, despite reviewer ambivalence. Future research should study barriers to adopting automated tools and how highly educated and experienced researchers can adapt to a job market that is increasingly challenged by new technologies.
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spelling doaj.art-6ff612c2b4744404b5ddf27a8fa5349c2022-12-22T03:27:33ZengBMCBMC Medical Research Methodology1471-22882022-06-0122111210.1186/s12874-022-01649-yAutomating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning systemPatricia Sofia Jacobsen Jardim0Christopher James Rose1Heather Melanie Ames2Jose Francisco Meneses Echavez3Stijn Van de Velde4Ashley Elizabeth Muller5Division for Health Services, Norwegian Institute of Public HealthDivision for Health Services, Norwegian Institute of Public HealthDivision for Health Services, Norwegian Institute of Public HealthDivision for Health Services, Norwegian Institute of Public HealthDivision for Health Services, Norwegian Institute of Public HealthDivision for Health Services, Norwegian Institute of Public HealthAbstract Background Machine learning and automation are increasingly used to make the evidence synthesis process faster and more responsive to policymakers’ needs. In systematic reviews of randomized controlled trials (RCTs), risk of bias assessment is a resource-intensive task that typically requires two trained reviewers. One function of RobotReviewer, an off-the-shelf machine learning system, is an automated risk of bias assessment. Methods We assessed the feasibility of adopting RobotReviewer within a national public health institute using a randomized, real-time, user-centered study. The study included 26 RCTs and six reviewers from two projects examining health and social interventions. We randomized these studies to one of two RobotReviewer platforms. We operationalized feasibility as accuracy, time use, and reviewer acceptability. We measured accuracy by the number of corrections made by human reviewers (either to automated assessments or another human reviewer’s assessments). We explored acceptability through group discussions and individual email responses after presenting the quantitative results. Results Reviewers were equally likely to accept judgment by RobotReviewer as each other’s judgement during the consensus process when measured dichotomously; risk ratio 1.02 (95% CI 0.92 to 1.13; p = 0.33). We were not able to compare time use. The acceptability of the program by researchers was mixed. Less experienced reviewers were generally more positive, and they saw more benefits and were able to use the tool more flexibly. Reviewers positioned human input and human-to-human interaction as superior to even a semi-automation of this process. Conclusion Despite being presented with evidence of RobotReviewer’s equal performance to humans, participating reviewers were not interested in modifying standard procedures to include automation. If further studies confirm equal accuracy and reduced time compared to manual practices, we suggest that the benefits of RobotReviewer may support its future implementation as one of two assessors, despite reviewer ambivalence. Future research should study barriers to adopting automated tools and how highly educated and experienced researchers can adapt to a job market that is increasingly challenged by new technologies.https://doi.org/10.1186/s12874-022-01649-yRisk of biasMachine learningAutomationEvidence synthesisSystematic reviewHeath technology assessment
spellingShingle Patricia Sofia Jacobsen Jardim
Christopher James Rose
Heather Melanie Ames
Jose Francisco Meneses Echavez
Stijn Van de Velde
Ashley Elizabeth Muller
Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
BMC Medical Research Methodology
Risk of bias
Machine learning
Automation
Evidence synthesis
Systematic review
Heath technology assessment
title Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
title_full Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
title_fullStr Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
title_full_unstemmed Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
title_short Automating risk of bias assessment in systematic reviews: a real-time mixed methods comparison of human researchers to a machine learning system
title_sort automating risk of bias assessment in systematic reviews a real time mixed methods comparison of human researchers to a machine learning system
topic Risk of bias
Machine learning
Automation
Evidence synthesis
Systematic review
Heath technology assessment
url https://doi.org/10.1186/s12874-022-01649-y
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