The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial)
Background Solar lentigines are skin lesions manifested by benign dark pigmentation causing a cosmetic problem in many patients. Several treatment modalities used for the management of solar lentigines. Side effects and rates of recurrence may be associated with them. Objective Treating solar lentig...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-01-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2020.1755415 |
| _version_ | 1797683614198005760 |
|---|---|
| author | Naeim Abd.El-Naby Mai Mostafa Ali Soha Abdalla Hawwam Naglaa Sarhan |
| author_facet | Naeim Abd.El-Naby Mai Mostafa Ali Soha Abdalla Hawwam Naglaa Sarhan |
| author_sort | Naeim Abd.El-Naby |
| collection | DOAJ |
| description | Background Solar lentigines are skin lesions manifested by benign dark pigmentation causing a cosmetic problem in many patients. Several treatment modalities used for the management of solar lentigines. Side effects and rates of recurrence may be associated with them. Objective Treating solar lentigines with two different techniques of pulsed dye laser (PDL) and evaluation of the results both clinically and via the examination of ultrastructural changes by electron microscopy. Patients and methods This study was conducted on 22 subjects with solar lentigines and having Fitzpatrick III–IV skin types, was managed by the use of PDL after enrolling them into two groups. Group I (one stacked PDL was used) and Group II (treated by stacked PDL in two sessions, 1 month apart). At baseline and 6 months after treatment, two punch biopsies with a diameter of 2 mm were taken from all patients. All taken biopsies were prepared for light and electron microscopic examinations. Results Both PDL techniques induced significant better clinical and histological outcomes. No one demonstrated any postoperative complications such as post-inflammatory hyperpigmentation and scarring. Conclusions The two techniques of PDL are efficient for solar lentigines treatment. |
| first_indexed | 2024-03-12T00:17:03Z |
| format | Article |
| id | doaj.art-6ff97bd6adfe448cae6402402275a4c0 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:17:03Z |
| publishDate | 2022-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-6ff97bd6adfe448cae6402402275a4c02023-09-15T14:23:05ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532022-01-0133136136810.1080/09546634.2020.17554151755415The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial)Naeim Abd.El-Naby0Mai Mostafa Ali1Soha Abdalla Hawwam2Naglaa Sarhan3Dermatology and Venereology Department, Faculty of Medicine, Tanta UniversityDermatology and Venereology Department, Faculty of Medicine, Tanta UniversityDermatology and Venereology Department, Faculty of Medicine, Tanta UniversityHistology Department, Faculty of Medicine, Tanta UniversityBackground Solar lentigines are skin lesions manifested by benign dark pigmentation causing a cosmetic problem in many patients. Several treatment modalities used for the management of solar lentigines. Side effects and rates of recurrence may be associated with them. Objective Treating solar lentigines with two different techniques of pulsed dye laser (PDL) and evaluation of the results both clinically and via the examination of ultrastructural changes by electron microscopy. Patients and methods This study was conducted on 22 subjects with solar lentigines and having Fitzpatrick III–IV skin types, was managed by the use of PDL after enrolling them into two groups. Group I (one stacked PDL was used) and Group II (treated by stacked PDL in two sessions, 1 month apart). At baseline and 6 months after treatment, two punch biopsies with a diameter of 2 mm were taken from all patients. All taken biopsies were prepared for light and electron microscopic examinations. Results Both PDL techniques induced significant better clinical and histological outcomes. No one demonstrated any postoperative complications such as post-inflammatory hyperpigmentation and scarring. Conclusions The two techniques of PDL are efficient for solar lentigines treatment.http://dx.doi.org/10.1080/09546634.2020.1755415pulsed dye laserelectron microscopesolar lentiginesultrastuctural study |
| spellingShingle | Naeim Abd.El-Naby Mai Mostafa Ali Soha Abdalla Hawwam Naglaa Sarhan The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) Journal of Dermatological Treatment pulsed dye laser electron microscope solar lentigines ultrastuctural study |
| title | The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) |
| title_full | The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) |
| title_fullStr | The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) |
| title_full_unstemmed | The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) |
| title_short | The clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines (randomized clinical trial) |
| title_sort | clinical and electron microscopic evaluation of the impact of pulsed dye laser techniques on solar lentigines randomized clinical trial |
| topic | pulsed dye laser electron microscope solar lentigines ultrastuctural study |
| url | http://dx.doi.org/10.1080/09546634.2020.1755415 |
| work_keys_str_mv | AT naeimabdelnaby theclinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT maimostafaali theclinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT sohaabdallahawwam theclinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT naglaasarhan theclinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT naeimabdelnaby clinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT maimostafaali clinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT sohaabdallahawwam clinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial AT naglaasarhan clinicalandelectronmicroscopicevaluationoftheimpactofpulseddyelasertechniquesonsolarlentiginesrandomizedclinicaltrial |