Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model
Background: Increased oxidative stress in women with polycystic ovary syndrome attracted attentions to antioxidant treatments. Calligonum Comosum is a planet with antioxidant propertis. Objective: This study aimed to investigating Calligonum effect on polycystic ovarian histology of polycystic ovar...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Institue of Medicinal Plants, ACECR
2015-12-01
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| Series: | Journal of Medicinal Plants |
| Subjects: | |
| Online Access: | http://jmp.ir/article-1-913-en.html |
| _version_ | 1818647021409533952 |
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| author | L Amini N Tehranian M Movahedin F Ramezani Tehrani |
| author_facet | L Amini N Tehranian M Movahedin F Ramezani Tehrani |
| author_sort | L Amini |
| collection | DOAJ |
| description | Background: Increased oxidative stress in women with polycystic ovary syndrome attracted attentions to antioxidant treatments. Calligonum Comosum is a planet with antioxidant propertis.
Objective: This study aimed to investigating Calligonum effect on polycystic ovarian histology of polycystic ovary mouse model.
Methods: Thity two female NMRI mice with 25-30 gr weight and 8 weeks age were investigated. A single dose of estradiol valerate (40 mg/kg; im) was used for induce polycystic ovarian morphology. Calligonum Comosom extract (20 mg/kg/ week; ip) was injected for 4 consequent weeks. In sham group, only DMSO was used. After 4 weeks, blood and histological samples were prepared to study.
Results: There was no significant effect of 20 mg/kg Calligonum on polycystic ovarian morphology mouse model.
Conclusion: The effect of other doses of Calligonum Comosum on fertility or adverse effect of this planet need to be more investigated. |
| first_indexed | 2024-12-17T00:55:54Z |
| format | Article |
| id | doaj.art-6ffd937f369d4b889bd94d9aa19cbe84 |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-12-17T00:55:54Z |
| publishDate | 2015-12-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-6ffd937f369d4b889bd94d9aa19cbe842022-12-21T22:09:36ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582015-12-011456115122Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse modelL Amini0N Tehranian1M Movahedin2F Ramezani Tehrani3 PhD candidate of Reproductive Health, Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences Background: Increased oxidative stress in women with polycystic ovary syndrome attracted attentions to antioxidant treatments. Calligonum Comosum is a planet with antioxidant propertis. Objective: This study aimed to investigating Calligonum effect on polycystic ovarian histology of polycystic ovary mouse model. Methods: Thity two female NMRI mice with 25-30 gr weight and 8 weeks age were investigated. A single dose of estradiol valerate (40 mg/kg; im) was used for induce polycystic ovarian morphology. Calligonum Comosom extract (20 mg/kg/ week; ip) was injected for 4 consequent weeks. In sham group, only DMSO was used. After 4 weeks, blood and histological samples were prepared to study. Results: There was no significant effect of 20 mg/kg Calligonum on polycystic ovarian morphology mouse model. Conclusion: The effect of other doses of Calligonum Comosum on fertility or adverse effect of this planet need to be more investigated.http://jmp.ir/article-1-913-en.htmlcalligonum comosumanimal model of polycystic ovaryeskanbilpolycystic ovarian morphology |
| spellingShingle | L Amini N Tehranian M Movahedin F Ramezani Tehrani Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model Journal of Medicinal Plants calligonum comosum animal model of polycystic ovary eskanbil polycystic ovarian morphology |
| title | Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model |
| title_full | Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model |
| title_fullStr | Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model |
| title_full_unstemmed | Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model |
| title_short | Effect of Calligonum Comosum on Ovarian Histology of Polycystic Ovary mouse model |
| title_sort | effect of calligonum comosum on ovarian histology of polycystic ovary mouse model |
| topic | calligonum comosum animal model of polycystic ovary eskanbil polycystic ovarian morphology |
| url | http://jmp.ir/article-1-913-en.html |
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