Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report
An 11-year-old male Cocker Spaniel was examined for a palpable abdominal mass located in the jejunum after presenting with a history of anorexia and constipation for several weeks. In a contrast radiogram, a structure with well-defined borders adjacent to the intestine was determined. The intestinal...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2012-06-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-201206-0007_primary-intestinal-fibrosarcoma-caused-by-intestinal-perforation-in-a-dog-a-case-report.php |
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| author | H. Avci R. Yaygingul M. Gultekin E.T. Epikmen K. Ural A. Belge S.S. Birincioglu |
| author_facet | H. Avci R. Yaygingul M. Gultekin E.T. Epikmen K. Ural A. Belge S.S. Birincioglu |
| author_sort | H. Avci |
| collection | DOAJ |
| description | An 11-year-old male Cocker Spaniel was examined for a palpable abdominal mass located in the jejunum after presenting with a history of anorexia and constipation for several weeks. In a contrast radiogram, a structure with well-defined borders adjacent to the intestine was determined. The intestinal mass, measuring 16 × 9.19 × 8.6 cm and weighing 900 g was surgically removed. At gross examination, when the lumen of a portion of the intestine excised together with the tumour mass was exposed, an ulcerated, oval-shaped area 1.2 × 0.6 cm in size was observed on the mucosa. The outer surface of the tumour was homogenous and expanded outwards from the intestinal wall. Histologically, the tumour was composed of fusiform-elongated spindle-shaped to polygonal neoplastic cells forming interlacing fascicles or interwoven bundles in an atypical herringbone pattern. Immnunohistochemically, neoplastic cells stained intensely positive for vimentin, and negative for α-SMA, desmin, cyotokeratin (AE1/AE3), S-100 protein, glial fibrillary acidic protein, neuron specific enolase and synaptophsin. On the basis of the histopathological and immunohistochemical results, the tumour was diagnosed as a fibrosarcoma. The present report is a very rare description of fibrosarcoma of the dog intestine associated with intestinal perforation. |
| first_indexed | 2024-04-10T08:00:46Z |
| format | Article |
| id | doaj.art-700434312f2d4b0d9254ca4e34c9116f |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:00:46Z |
| publishDate | 2012-06-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-700434312f2d4b0d9254ca4e34c9116f2023-02-23T03:50:02ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922012-06-0157631431910.17221/6019-VETMEDvet-201206-0007Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case reportH. Avci0R. Yaygingul1M. Gultekin2E.T. Epikmen3K. Ural4A. Belge5S.S. Birincioglu6Faculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyFaculty of Veterinary Medicine, University of Adnan Menderes, Aydin, TurkeyAn 11-year-old male Cocker Spaniel was examined for a palpable abdominal mass located in the jejunum after presenting with a history of anorexia and constipation for several weeks. In a contrast radiogram, a structure with well-defined borders adjacent to the intestine was determined. The intestinal mass, measuring 16 × 9.19 × 8.6 cm and weighing 900 g was surgically removed. At gross examination, when the lumen of a portion of the intestine excised together with the tumour mass was exposed, an ulcerated, oval-shaped area 1.2 × 0.6 cm in size was observed on the mucosa. The outer surface of the tumour was homogenous and expanded outwards from the intestinal wall. Histologically, the tumour was composed of fusiform-elongated spindle-shaped to polygonal neoplastic cells forming interlacing fascicles or interwoven bundles in an atypical herringbone pattern. Immnunohistochemically, neoplastic cells stained intensely positive for vimentin, and negative for α-SMA, desmin, cyotokeratin (AE1/AE3), S-100 protein, glial fibrillary acidic protein, neuron specific enolase and synaptophsin. On the basis of the histopathological and immunohistochemical results, the tumour was diagnosed as a fibrosarcoma. The present report is a very rare description of fibrosarcoma of the dog intestine associated with intestinal perforation.https://vetmed.agriculturejournals.cz/artkey/vet-201206-0007_primary-intestinal-fibrosarcoma-caused-by-intestinal-perforation-in-a-dog-a-case-report.phpdogfibrosarcomaintestinepathology |
| spellingShingle | H. Avci R. Yaygingul M. Gultekin E.T. Epikmen K. Ural A. Belge S.S. Birincioglu Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report Veterinární Medicína dog fibrosarcoma intestine pathology |
| title | Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report |
| title_full | Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report |
| title_fullStr | Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report |
| title_full_unstemmed | Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report |
| title_short | Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report |
| title_sort | primary intestinal fibrosarcoma caused by intestinal perforation in a dog a case report |
| topic | dog fibrosarcoma intestine pathology |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-201206-0007_primary-intestinal-fibrosarcoma-caused-by-intestinal-perforation-in-a-dog-a-case-report.php |
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