Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19

Abstract An Adaptive Susceptible-Infected-Removed-Vaccinated (A-SIRV) epidemic model with time-dependent transmission and removal rates is constructed for investigating the dynamics of an epidemic disease such as the COVID-19 pandemic. Real data of COVID-19 spread is used for the simultaneous identi...

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Main Authors: Tchavdar T. Marinov, Rossitza S. Marinova
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20276-7
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author Tchavdar T. Marinov
Rossitza S. Marinova
author_facet Tchavdar T. Marinov
Rossitza S. Marinova
author_sort Tchavdar T. Marinov
collection DOAJ
description Abstract An Adaptive Susceptible-Infected-Removed-Vaccinated (A-SIRV) epidemic model with time-dependent transmission and removal rates is constructed for investigating the dynamics of an epidemic disease such as the COVID-19 pandemic. Real data of COVID-19 spread is used for the simultaneous identification of the unknown time-dependent rates and functions participating in the A-SIRV system. The inverse problem is formulated and solved numerically using the Method of Variational Imbedding, which reduces the inverse problem to a problem for minimizing a properly constructed functional for obtaining the sought values. To illustrate and validate the proposed solution approach, the present study used available public data for several countries with diverse population and vaccination dynamics—the World, Israel, The United States of America, and Japan.
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spelling doaj.art-70098895e7cb4965ae593b23195219a52022-12-22T04:25:56ZengNature PortfolioScientific Reports2045-23222022-09-0112111310.1038/s41598-022-20276-7Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19Tchavdar T. Marinov0Rossitza S. Marinova1Department of Natural Sciences, Southern University at New OrleansDepartment of Mathematical and Physical Sciences, Concordia University of EdmontonAbstract An Adaptive Susceptible-Infected-Removed-Vaccinated (A-SIRV) epidemic model with time-dependent transmission and removal rates is constructed for investigating the dynamics of an epidemic disease such as the COVID-19 pandemic. Real data of COVID-19 spread is used for the simultaneous identification of the unknown time-dependent rates and functions participating in the A-SIRV system. The inverse problem is formulated and solved numerically using the Method of Variational Imbedding, which reduces the inverse problem to a problem for minimizing a properly constructed functional for obtaining the sought values. To illustrate and validate the proposed solution approach, the present study used available public data for several countries with diverse population and vaccination dynamics—the World, Israel, The United States of America, and Japan.https://doi.org/10.1038/s41598-022-20276-7
spellingShingle Tchavdar T. Marinov
Rossitza S. Marinova
Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
Scientific Reports
title Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
title_full Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
title_fullStr Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
title_full_unstemmed Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
title_short Adaptive SIR model with vaccination: simultaneous identification of rates and functions illustrated with COVID-19
title_sort adaptive sir model with vaccination simultaneous identification of rates and functions illustrated with covid 19
url https://doi.org/10.1038/s41598-022-20276-7
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