A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/18/1/1255 |
| _version_ | 1819127415446700032 |
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| author | Zhang-Hua Sun Ning-Hua Tan Lin Xiao Guang-Zhi Zeng Jian Xu Yu-Mei Zhang |
| author_facet | Zhang-Hua Sun Ning-Hua Tan Lin Xiao Guang-Zhi Zeng Jian Xu Yu-Mei Zhang |
| author_sort | Zhang-Hua Sun |
| collection | DOAJ |
| description | A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC50 values were 6.9, 29.7 and 52.9 μM, respectively. |
| first_indexed | 2024-12-22T08:11:34Z |
| format | Article |
| id | doaj.art-700e20aa2a9545dcaea5555098eef62c |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-22T08:11:34Z |
| publishDate | 2013-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-700e20aa2a9545dcaea5555098eef62c2022-12-21T18:33:00ZengMDPI AGMolecules1420-30492013-01-011811255126110.3390/molecules18011255A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsiiZhang-Hua SunNing-Hua TanLin XiaoGuang-Zhi ZengJian XuYu-Mei ZhangA new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC50 values were 6.9, 29.7 and 52.9 μM, respectively.http://www.mdpi.com/1420-3049/18/1/1255Chamaecyparis obtusa var. breviramea f. crippsiiphenolic compoundscytotoxicity |
| spellingShingle | Zhang-Hua Sun Ning-Hua Tan Lin Xiao Guang-Zhi Zeng Jian Xu Yu-Mei Zhang A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii Molecules Chamaecyparis obtusa var. breviramea f. crippsii phenolic compounds cytotoxicity |
| title | A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii |
| title_full | A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii |
| title_fullStr | A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii |
| title_full_unstemmed | A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii |
| title_short | A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii |
| title_sort | new phenolic glycoside from chamaecyparis obtusa var breviramea f crippsii |
| topic | Chamaecyparis obtusa var. breviramea f. crippsii phenolic compounds cytotoxicity |
| url | http://www.mdpi.com/1420-3049/18/1/1255 |
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