Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019

We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with blaOXA-181 and differed by 0–32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characteriz...

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Main Authors: Appiah-Korang Labi, Karen L. Nielsen, Rasmus L. Marvig, Stephanie Bjerrum, Christabel Enweronu-Laryea, Marc Bennedbæk, Mercy J. Newman, Prosper K. Ayibor, Leif P. Andersen, Jørgen A.L. Kurtzhals
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-09-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/26/9/20-0562_article
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author Appiah-Korang Labi
Karen L. Nielsen
Rasmus L. Marvig
Stephanie Bjerrum
Christabel Enweronu-Laryea
Marc Bennedbæk
Mercy J. Newman
Prosper K. Ayibor
Leif P. Andersen
Jørgen A.L. Kurtzhals
author_facet Appiah-Korang Labi
Karen L. Nielsen
Rasmus L. Marvig
Stephanie Bjerrum
Christabel Enweronu-Laryea
Marc Bennedbæk
Mercy J. Newman
Prosper K. Ayibor
Leif P. Andersen
Jørgen A.L. Kurtzhals
author_sort Appiah-Korang Labi
collection DOAJ
description We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with blaOXA-181 and differed by 0–32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characterize and curb the spread of multidrug-resistant organisms in sub-Saharan Africa.
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spelling doaj.art-700f243fa65a4faca948fa7012918b292022-12-21T22:44:56ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592020-09-012692235223810.3201/eid2609.200562Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019Appiah-Korang LabiKaren L. NielsenRasmus L. MarvigStephanie BjerrumChristabel Enweronu-LaryeaMarc BennedbækMercy J. NewmanProsper K. AyiborLeif P. AndersenJørgen A.L. KurtzhalsWe sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with blaOXA-181 and differed by 0–32 single-nucleotide polymorphisms. Improved surveillance and infection control are needed to characterize and curb the spread of multidrug-resistant organisms in sub-Saharan Africa.https://wwwnc.cdc.gov/eid/article/26/9/20-0562_articleneonatal intensive care unitGhanaKlebsiella pneumoniaewhole-genome sequencingbloodstream infectioncarbapenemase-producing
spellingShingle Appiah-Korang Labi
Karen L. Nielsen
Rasmus L. Marvig
Stephanie Bjerrum
Christabel Enweronu-Laryea
Marc Bennedbæk
Mercy J. Newman
Prosper K. Ayibor
Leif P. Andersen
Jørgen A.L. Kurtzhals
Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
Emerging Infectious Diseases
neonatal intensive care unit
Ghana
Klebsiella pneumoniae
whole-genome sequencing
bloodstream infection
carbapenemase-producing
title Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
title_full Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
title_fullStr Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
title_full_unstemmed Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
title_short Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019
title_sort oxacillinase 181 carbapenemase producing klebsiella pneumoniae in neonatal intensive care unit ghana 2017 2019
topic neonatal intensive care unit
Ghana
Klebsiella pneumoniae
whole-genome sequencing
bloodstream infection
carbapenemase-producing
url https://wwwnc.cdc.gov/eid/article/26/9/20-0562_article
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