Antibiotic prescriptions for oral diseases in India: evidence from national prescription data

Abstract Introduction The key objective of this research was to describe the prescription rate of various antibiotics for dental problems in India and to study the relevance of the prescriptions by analysing antibiotic types associated with different dental diagnoses, using a large-scale nationally...

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Main Authors: Manu Raj Mathur, Deepti Nagrath, Vijay Kumar Mishra, Rebecca Harris, Syed Saif Saeed, Sakthivel Selvaraj, Aashna Mehta, Habib Hasan Farooqui
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-023-02889-0
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author Manu Raj Mathur
Deepti Nagrath
Vijay Kumar Mishra
Rebecca Harris
Syed Saif Saeed
Sakthivel Selvaraj
Aashna Mehta
Habib Hasan Farooqui
author_facet Manu Raj Mathur
Deepti Nagrath
Vijay Kumar Mishra
Rebecca Harris
Syed Saif Saeed
Sakthivel Selvaraj
Aashna Mehta
Habib Hasan Farooqui
author_sort Manu Raj Mathur
collection DOAJ
description Abstract Introduction The key objective of this research was to describe the prescription rate of various antibiotics for dental problems in India and to study the relevance of the prescriptions by analysing antibiotic types associated with different dental diagnoses, using a large-scale nationally representative dataset. Methods We used a 12-month period (May 2015 to April 2016) medical audit dataset from IQVIA (formerly IMS Health). We coded the dental diagnosis provided in the medical audit data to the International Statistical Classification of Diseases and Related Health Problems (ICD-11) and the prescribed antibiotics for the diagnosis to the Anatomic Therapeutic Chemical (ATC) -2020 classification of the World Health Organization. The primary outcome measure was the medicine prescription rate per 1,000 persons per year (PRPY1000). Results Our main findings were—403 prescriptions per 1,000 persons per year in the year 2015 -2016 for all dental ailments. Across all ATC level 1 classification, ‘Diseases of hard tissues’ made up the majority of the prescriptions. ‘Beta-lactam’, ‘Penicillin,’ and ‘Cephalosporins’ were the most commonly prescribed antibiotics for dental diagnoses followed by ‘Macrolides’ and ‘Quinolones’. ‘Dental caries’, ‘Discoloration of tooth’, and ‘Toothache’ were the most common reasons for ‘Beta-Lactams’ and ‘Penicillin’ prescriptions. Conclusion To conclude our study reports first ever country (India) level estimates of antibiotic prescription by antibiotic classes, age groups, and ICD-11 classification for dental ailments.
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spelling doaj.art-700fa3024e3848129ffa1e5d4aacab632023-03-26T11:18:55ZengBMCBMC Oral Health1472-68312023-03-012311810.1186/s12903-023-02889-0Antibiotic prescriptions for oral diseases in India: evidence from national prescription dataManu Raj Mathur0Deepti Nagrath1Vijay Kumar Mishra2Rebecca Harris3Syed Saif Saeed4Sakthivel Selvaraj5Aashna Mehta6Habib Hasan Farooqui7Queen Mary University of LondonPublic Health Foundation of IndiaPublic Health Foundation of IndiaUniversity of LiverpoolUniversity College LondonHealth Economics, Financing and Policy, Public Health Foundation of IndiaPublic Health Foundation of IndiaCollege of Medicine, QU Health, Qatar UniversityAbstract Introduction The key objective of this research was to describe the prescription rate of various antibiotics for dental problems in India and to study the relevance of the prescriptions by analysing antibiotic types associated with different dental diagnoses, using a large-scale nationally representative dataset. Methods We used a 12-month period (May 2015 to April 2016) medical audit dataset from IQVIA (formerly IMS Health). We coded the dental diagnosis provided in the medical audit data to the International Statistical Classification of Diseases and Related Health Problems (ICD-11) and the prescribed antibiotics for the diagnosis to the Anatomic Therapeutic Chemical (ATC) -2020 classification of the World Health Organization. The primary outcome measure was the medicine prescription rate per 1,000 persons per year (PRPY1000). Results Our main findings were—403 prescriptions per 1,000 persons per year in the year 2015 -2016 for all dental ailments. Across all ATC level 1 classification, ‘Diseases of hard tissues’ made up the majority of the prescriptions. ‘Beta-lactam’, ‘Penicillin,’ and ‘Cephalosporins’ were the most commonly prescribed antibiotics for dental diagnoses followed by ‘Macrolides’ and ‘Quinolones’. ‘Dental caries’, ‘Discoloration of tooth’, and ‘Toothache’ were the most common reasons for ‘Beta-Lactams’ and ‘Penicillin’ prescriptions. Conclusion To conclude our study reports first ever country (India) level estimates of antibiotic prescription by antibiotic classes, age groups, and ICD-11 classification for dental ailments.https://doi.org/10.1186/s12903-023-02889-0Antimicrobial ResistanceIndiaDental AilmentsPrescription Rates
spellingShingle Manu Raj Mathur
Deepti Nagrath
Vijay Kumar Mishra
Rebecca Harris
Syed Saif Saeed
Sakthivel Selvaraj
Aashna Mehta
Habib Hasan Farooqui
Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
BMC Oral Health
Antimicrobial Resistance
India
Dental Ailments
Prescription Rates
title Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
title_full Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
title_fullStr Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
title_full_unstemmed Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
title_short Antibiotic prescriptions for oral diseases in India: evidence from national prescription data
title_sort antibiotic prescriptions for oral diseases in india evidence from national prescription data
topic Antimicrobial Resistance
India
Dental Ailments
Prescription Rates
url https://doi.org/10.1186/s12903-023-02889-0
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