Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
uvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2012-10-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/611 |
| _version_ | 1797873036922191872 |
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| author | V. O. Roschina V. D. Zavadovskaya N. G. Zaviyalova A. N. Kailina Yu. P. Chasovskikh |
| author_facet | V. O. Roschina V. D. Zavadovskaya N. G. Zaviyalova A. N. Kailina Yu. P. Chasovskikh |
| author_sort | V. O. Roschina |
| collection | DOAJ |
| description | uvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural changes in knee joints, 25 children with JIA were passed through ultrasonic examination with the use of 7.5—11 (14) MHz linear sensors in superscale mode with energy and color Doppler mapping. Standard laboratory indices, rheumatoid factor (RF), and modified citrullinated vimentin antibodies (MCVA) in blood serum by the ELISA method were determined as well. The JIA activity was assessed using the DAS28 index. In the examination of knee joints in the group with JIA, most characteristic changes were uniform synovium thickening (68% of cases) with proliferation and vascularization (in 50% at proliferation), joint capsule effusion (56% cases) with mean values of (4.16 ± 2.47) mm. Reliable correlation has been revealed between synovium vascularization and MCVA level, erythrocyte sedimentation rate, and DAS28 activity, as well as thickness of joint effusion with MCVA level. |
| first_indexed | 2024-04-10T01:08:42Z |
| format | Article |
| id | doaj.art-70116b8dbdac469a9de2b8973f7c33dd |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:08:42Z |
| publishDate | 2012-10-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-70116b8dbdac469a9de2b8973f7c33dd2023-03-13T09:58:17ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-10-01115162210.20538/1682-0363-2012-5-16-22556Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritisV. O. Roschina0V. D. Zavadovskaya1N. G. Zaviyalova2A. N. Kailina3Yu. P. Chasovskikh4МБЛПУ «Детская городская больница № 1», г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. Томскuvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural changes in knee joints, 25 children with JIA were passed through ultrasonic examination with the use of 7.5—11 (14) MHz linear sensors in superscale mode with energy and color Doppler mapping. Standard laboratory indices, rheumatoid factor (RF), and modified citrullinated vimentin antibodies (MCVA) in blood serum by the ELISA method were determined as well. The JIA activity was assessed using the DAS28 index. In the examination of knee joints in the group with JIA, most characteristic changes were uniform synovium thickening (68% of cases) with proliferation and vascularization (in 50% at proliferation), joint capsule effusion (56% cases) with mean values of (4.16 ± 2.47) mm. Reliable correlation has been revealed between synovium vascularization and MCVA level, erythrocyte sedimentation rate, and DAS28 activity, as well as thickness of joint effusion with MCVA level.https://bulletin.ssmu.ru/jour/article/view/611ювенильный идиопатический артритантитела к модифицированному цитруллинированному виментинуревматоидный факторультрасонография коленных суставов |
| spellingShingle | V. O. Roschina V. D. Zavadovskaya N. G. Zaviyalova A. N. Kailina Yu. P. Chasovskikh Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis Бюллетень сибирской медицины ювенильный идиопатический артрит антитела к модифицированному цитруллинированному виментину ревматоидный фактор ультрасонография коленных суставов |
| title | Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis |
| title_full | Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis |
| title_fullStr | Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis |
| title_full_unstemmed | Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis |
| title_short | Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis |
| title_sort | role of ultrasonic examination in assessment of the knee joint state in patients with juvenile idiopathic arthritis |
| topic | ювенильный идиопатический артрит антитела к модифицированному цитруллинированному виментину ревматоидный фактор ультрасонография коленных суставов |
| url | https://bulletin.ssmu.ru/jour/article/view/611 |
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