Effects of Elexacaftor/Tezacaftor/Ivacaftor on Cardiorespiratory Polygraphy Parameters and Respiratory Muscle Strength in Cystic Fibrosis Patients with Severe Lung Disease

Effects of Elexacaftor/Tezacaftor/Ivacaftor on Cardiorespiratory Polygraphy Parameters and Respiratory Muscle Strength in Cystic Fibrosis Patients with Severe Lung Disease

Background: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators represent targeted therapies directly acting on the CFTR channel. The triple therapy Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) has been demonstrated to improve lung function and quality of life in cystic fibrosis...

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Bibliographic Details
Main Authors: Alessandro Giallongo, Giuseppe Fabio Parisi, Maria Papale, Sara Manti, Enza Mulé, Donatella Aloisio, Vito Terlizzi, Novella Rotolo, Salvatore Leonardi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Genes
Subjects:
cystic fibrosis
elexacaftor/tezacaftor/ivacaftor
CFTR
modulators
cardiorespiratory polygraphy
Online Access:https://www.mdpi.com/2073-4425/14/2/449

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