Functional Variant rs3135500 in NOD2 Increases the Risk of Multiple System Atrophy in a Chinese Population

Functional Variant rs3135500 in NOD2 Increases the Risk of Multiple System Atrophy in a Chinese Population

Background: Given the overlap of clinical manifestations and pathological characteristics between Parkinson's disease (PD) and multiple system atrophy (MSA), we investigated the associations between five functional polymorphisms of nucleotide-binding oligomerization domain protein 2 (NOD2) whic...

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Bibliographic Details
Main Authors: Bei Cao, Yongping Chen, Qingqing Zhou, Lingyu Zhang, Ruwei Ou, Qianqian Wei, Ying Wu, Hui-Fang Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
multiple system atrophy
NOD2
variants
expression
association
α-synuclein
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00150/full

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