A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.

A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.

Malignant gliomas remain incurable with a poor prognosis despite of aggressive treatment. We have been studying the development of brain tumors in a glioma rat model, where rats develop brain tumors after prenatal exposure to ethylnitrosourea (ENU), and there is a sizable interval between when the f...

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Bibliographic Details
Main Authors: Le Zheng, Yan Zhang, Shiying Hao, Lin Chen, Zhen Sun, Chi Yan, John C Whitin, Taichang Jang, Milton Merchant, Doff B McElhinney, Karl G Sylvester, Harvey J Cohen, Lawrence Recht, Xiaoming Yao, Xuefeng B Ling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223558

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