Prediction of the Molecular Subtype of IDH Mutation Combined with MGMT Promoter Methylation in Gliomas via Radiomics Based on Preoperative MRI

Prediction of the Molecular Subtype of IDH Mutation Combined with MGMT Promoter Methylation in Gliomas via Radiomics Based on Preoperative MRI

Background: The molecular subtype of IDH mut combined with MGMT meth in gliomas suggests a good prognosis and potential benefit from TMZ chemotherapy. The aim of this study was to establish a radiomics model to predict this molecular subtype. Method: The preoperative MR images and genetic data of 49...

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Bibliographic Details
Main Authors: Yongjian Sha, Qianqian Yan, Yan Tan, Xiaochun Wang, Hui Zhang, Guoqiang Yang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
glioma
isocitrate dehydrogenase mutation (IDH mut)
O<sup>6</sup>-methylguanine-DNA methyltransferase promoter methylation (MGMT meth)
magnetic resonance imaging (MRI)
radiomics
Online Access:https://www.mdpi.com/2072-6694/15/5/1440

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