Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer
Background: Breast cancer has a high prevalence in Egyptian women representing a major health problem for the patients and the community. Mammography is the primary modality in breast imaging inspite of its well-known limitations. Currently, digital breast tomosynthesis is state-of-the-art modality...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2015-12-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X15001278 |
| _version_ | 1818281195418419200 |
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| author | Rania Refaat Mohammed Moh. Matar |
| author_facet | Rania Refaat Mohammed Moh. Matar |
| author_sort | Rania Refaat |
| collection | DOAJ |
| description | Background: Breast cancer has a high prevalence in Egyptian women representing a major health problem for the patients and the community. Mammography is the primary modality in breast imaging inspite of its well-known limitations. Currently, digital breast tomosynthesis is state-of-the-art modality in breast imaging which provides images reconstructed from multiple projections acquired at different angles.
Objective: To compare digital breast tomosynthesis (DBT) to digital mammography (DM) in a series of Egyptian women with pathologically proven breast cancer.
Materials and methods: Twenty five women who were imaged by DBT and DM, and were proved to have breast cancer, were enrolled in this study. The acquired images of DBT and DM were reviewed for the malignant features and for Breast Imaging-Reporting and Data System (BI-RADS) category assessment. The equivalence (i.e., better, equivalent or worse) of the malignant features in DBT compared to DM was also rated. Lesion detection by craniocaudal (CC) and mediolateral oblique (MLO) views was also compared.
Results: The equivalence rate of DBT compared to DM was superior in 60% of lesions (95% confidence interval [CI]; 44.1–75.9%); 11 of 20 (55%) mass lesions, 3 of 4 (75%) focal density lesions, 2 of 5 (40%) architectural distortion lesions and 8 of 11 (72.7%) in microcalcification lesions. Moreover, lesion detection by DBT was statistically significant (p = 0.008) in 7 lesions; 4 mass lesions, 1 architectural distortion lesion and 2 microcalcification lesions. Regarding BI-RADS category assessment, category increased rating by DBT compared to DM showed high statistical significance (p = 0.001). In addition, the superior equivalence rating of lesion detection by CC view compared to MLO view was statistically significant (p = 0.040).
Conclusion: Digital breast tomosynthesis provides more lesion detection and hence, it is better in assigning BI-RADS category by solving the difficulties of diagnosis caused by parenchyma overlap. |
| first_indexed | 2024-12-13T00:01:16Z |
| format | Article |
| id | doaj.art-70209e3b9dd147859dbf9cc3f6995d1a |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-13T00:01:16Z |
| publishDate | 2015-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-70209e3b9dd147859dbf9cc3f6995d1a2022-12-22T00:06:25ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2015-12-014641241124810.1016/j.ejrnm.2015.06.007Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancerRania Refaat0Mohammed Moh. Matar1Department of Radiodiagnosis, Ain Shams University, Cairo, EgyptDepartment of General Surgery, Ain Shams University, Cairo, EgyptBackground: Breast cancer has a high prevalence in Egyptian women representing a major health problem for the patients and the community. Mammography is the primary modality in breast imaging inspite of its well-known limitations. Currently, digital breast tomosynthesis is state-of-the-art modality in breast imaging which provides images reconstructed from multiple projections acquired at different angles. Objective: To compare digital breast tomosynthesis (DBT) to digital mammography (DM) in a series of Egyptian women with pathologically proven breast cancer. Materials and methods: Twenty five women who were imaged by DBT and DM, and were proved to have breast cancer, were enrolled in this study. The acquired images of DBT and DM were reviewed for the malignant features and for Breast Imaging-Reporting and Data System (BI-RADS) category assessment. The equivalence (i.e., better, equivalent or worse) of the malignant features in DBT compared to DM was also rated. Lesion detection by craniocaudal (CC) and mediolateral oblique (MLO) views was also compared. Results: The equivalence rate of DBT compared to DM was superior in 60% of lesions (95% confidence interval [CI]; 44.1–75.9%); 11 of 20 (55%) mass lesions, 3 of 4 (75%) focal density lesions, 2 of 5 (40%) architectural distortion lesions and 8 of 11 (72.7%) in microcalcification lesions. Moreover, lesion detection by DBT was statistically significant (p = 0.008) in 7 lesions; 4 mass lesions, 1 architectural distortion lesion and 2 microcalcification lesions. Regarding BI-RADS category assessment, category increased rating by DBT compared to DM showed high statistical significance (p = 0.001). In addition, the superior equivalence rating of lesion detection by CC view compared to MLO view was statistically significant (p = 0.040). Conclusion: Digital breast tomosynthesis provides more lesion detection and hence, it is better in assigning BI-RADS category by solving the difficulties of diagnosis caused by parenchyma overlap.http://www.sciencedirect.com/science/article/pii/S0378603X15001278Digital mammography (DM)Digital breast tomosynthesis (DBT)Breast Imaging-Reporting and Data System (BI-RADS)Pathologically proven breast cancerEgyptian women |
| spellingShingle | Rania Refaat Mohammed Moh. Matar Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer The Egyptian Journal of Radiology and Nuclear Medicine Digital mammography (DM) Digital breast tomosynthesis (DBT) Breast Imaging-Reporting and Data System (BI-RADS) Pathologically proven breast cancer Egyptian women |
| title | Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer |
| title_full | Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer |
| title_fullStr | Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer |
| title_full_unstemmed | Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer |
| title_short | Digital breast tomosynthesis compared to digital mammography in a series of Egyptian women with pathologically proven breast cancer |
| title_sort | digital breast tomosynthesis compared to digital mammography in a series of egyptian women with pathologically proven breast cancer |
| topic | Digital mammography (DM) Digital breast tomosynthesis (DBT) Breast Imaging-Reporting and Data System (BI-RADS) Pathologically proven breast cancer Egyptian women |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X15001278 |
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