Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines
Purpose This study compared the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS) for thyroid malignancy with three international guidelines. Methods From June to September 2015, 5,708 thyroid nodules (≥1.0 cm) in 5,081 consecutive patients who underw...
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| Format: | Article |
| Language: | English |
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Korean Society of Ultrasound in Medicine
2021-10-01
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| Series: | Ultrasonography |
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| Online Access: | http://www.e-ultrasonography.org/upload/usg-21056.pdf |
| _version_ | 1819122614348546048 |
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| author | Eun Ju Ha Jung Hee Shin Dong Gyu Na So Lyung Jung Young Hen Lee Wooyul Paik Min Ji Hong Yeo Koon Kim Chang Yoon Lee |
| author_facet | Eun Ju Ha Jung Hee Shin Dong Gyu Na So Lyung Jung Young Hen Lee Wooyul Paik Min Ji Hong Yeo Koon Kim Chang Yoon Lee |
| author_sort | Eun Ju Ha |
| collection | DOAJ |
| description | Purpose This study compared the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS) for thyroid malignancy with three international guidelines. Methods From June to September 2015, 5,708 thyroid nodules (≥1.0 cm) in 5,081 consecutive patients who underwent thyroid ultrasound (US) at 26 institutions were evaluated. The US features of the thyroid nodules were retrospectively reviewed and classified according to all four guidelines. In the modified K-TIRADS, the biopsy size threshold was changed to 2.0 cm for K-TIRADS 3 and 1.0 or 1.5 cm for K-TIRADS 4 (K-TIRADS1.0cm and K-TIRADS1.5cm, respectively). We compared the diagnostic performance and unnecessary fine-needle aspiration biopsy (FNAB) rates for thyroid malignancy between the modified K-TIRADS and three international guidelines. Results Of the 5,708 thyroid nodules, 4,597 (80.5%) were benign and 1,111 (19.5%) were malignant. The overall sensitivity was highest for the modified K-TIRADS1.0cm (91.0%), followed by the European (EU)-TIRADS (84.6%), American Association of Clinical Endocrinologists/American College of Endocrinology/Associazione Medici Endocrinologi (AACE/ACE/AME) (80.5%), American College of Radiology (ACR)-TIRADS (76.1%), and modified K-TIRADS1.5cm (76.1%). For large nodules (>2.0 cm), the sensitivity increased to 98.0% in both the modified K-TIRADS1.0cm and K-TIRADS1.5cm. For small nodules (≤2.0 cm), the unnecessary FNAB rate was lowest with the modified K-TIRADS1.5cm (17.6%), followed by the ACR-TIRADS (18.6%), AACE/ACE/AME (19.3%), EU-TIRADS (28.1%), and modified K-TIRADS1.0cm (31.2%). Conclusion The modified K-TIRADS1.5cm can reduce the unnecessary FNAB rate for small nodules (1.0-2.0 cm), while maintaining high sensitivity for detecting malignancies >2.0 cm. |
| first_indexed | 2024-12-22T06:55:15Z |
| format | Article |
| id | doaj.art-7022390dfd2f41e689ee453161acb4d9 |
| institution | Directory Open Access Journal |
| issn | 2288-5919 2288-5943 |
| language | English |
| last_indexed | 2024-12-22T06:55:15Z |
| publishDate | 2021-10-01 |
| publisher | Korean Society of Ultrasound in Medicine |
| record_format | Article |
| series | Ultrasonography |
| spelling | doaj.art-7022390dfd2f41e689ee453161acb4d92022-12-21T18:35:00ZengKorean Society of Ultrasound in MedicineUltrasonography2288-59192288-59432021-10-0140459460110.14366/usg.210561543Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelinesEun Ju Ha0Jung Hee Shin1Dong Gyu Na2So Lyung Jung3Young Hen Lee4Wooyul Paik5Min Ji Hong6Yeo Koon Kim7Chang Yoon Lee8 Department of Radiology, Ajou University School of Medicine, Suwon, Korea Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Radiology, GangNeung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea Department of Radiology, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea Department of Radiology, GangNeung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea Department of Radiology, Research Institute and Hospital, National Cancer Center, Goyang, KoreaPurpose This study compared the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS) for thyroid malignancy with three international guidelines. Methods From June to September 2015, 5,708 thyroid nodules (≥1.0 cm) in 5,081 consecutive patients who underwent thyroid ultrasound (US) at 26 institutions were evaluated. The US features of the thyroid nodules were retrospectively reviewed and classified according to all four guidelines. In the modified K-TIRADS, the biopsy size threshold was changed to 2.0 cm for K-TIRADS 3 and 1.0 or 1.5 cm for K-TIRADS 4 (K-TIRADS1.0cm and K-TIRADS1.5cm, respectively). We compared the diagnostic performance and unnecessary fine-needle aspiration biopsy (FNAB) rates for thyroid malignancy between the modified K-TIRADS and three international guidelines. Results Of the 5,708 thyroid nodules, 4,597 (80.5%) were benign and 1,111 (19.5%) were malignant. The overall sensitivity was highest for the modified K-TIRADS1.0cm (91.0%), followed by the European (EU)-TIRADS (84.6%), American Association of Clinical Endocrinologists/American College of Endocrinology/Associazione Medici Endocrinologi (AACE/ACE/AME) (80.5%), American College of Radiology (ACR)-TIRADS (76.1%), and modified K-TIRADS1.5cm (76.1%). For large nodules (>2.0 cm), the sensitivity increased to 98.0% in both the modified K-TIRADS1.0cm and K-TIRADS1.5cm. For small nodules (≤2.0 cm), the unnecessary FNAB rate was lowest with the modified K-TIRADS1.5cm (17.6%), followed by the ACR-TIRADS (18.6%), AACE/ACE/AME (19.3%), EU-TIRADS (28.1%), and modified K-TIRADS1.0cm (31.2%). Conclusion The modified K-TIRADS1.5cm can reduce the unnecessary FNAB rate for small nodules (1.0-2.0 cm), while maintaining high sensitivity for detecting malignancies >2.0 cm.http://www.e-ultrasonography.org/upload/usg-21056.pdffine-needle aspirationthyroid neoplasmsthyroid imaging reporting and data systemthyroid nodulesultrasonography |
| spellingShingle | Eun Ju Ha Jung Hee Shin Dong Gyu Na So Lyung Jung Young Hen Lee Wooyul Paik Min Ji Hong Yeo Koon Kim Chang Yoon Lee Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines Ultrasonography fine-needle aspiration thyroid neoplasms thyroid imaging reporting and data system thyroid nodules ultrasonography |
| title | Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines |
| title_full | Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines |
| title_fullStr | Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines |
| title_full_unstemmed | Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines |
| title_short | Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines |
| title_sort | comparison of the diagnostic performance of the modified korean thyroid imaging reporting and data system for thyroid malignancy with three international guidelines |
| topic | fine-needle aspiration thyroid neoplasms thyroid imaging reporting and data system thyroid nodules ultrasonography |
| url | http://www.e-ultrasonography.org/upload/usg-21056.pdf |
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