Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment
<p>Abstract</p> <p>Background</p> <p>Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological feat...
Main Authors: | Zhang Dake, Dong Peiling, Zhang Ke, Deng Libin, Bach Christian, Chen Wei, Li Feifei, Protzer Ulrike, Ding Huiguo, Zeng Changqing |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-12-01
|
Series: | BMC Microbiology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2180/12/307 |
Similar Items
-
Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections
by: Erik De Clercq, et al.
Published: (2010-05-01) -
The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles
by: Bingfu Jiang, et al.
Published: (2020-08-01) -
Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma
by: Jian-an Jia, et al.
Published: (2022-06-01) -
Tyrosine 146 of the Human Na<sup>+</sup>/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes
by: Dariusz Zakrzewicz, et al.
Published: (2022-06-01) -
Key Factors for “Fishing” NTCP as a Functional Receptor for HBV and HDV
by: Huan Yan, et al.
Published: (2023-02-01)