Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass

Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature du...

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Main Authors: Ali Rahdari, Reza Jalaeian Taghaddomi, Alireza Sabzevari, Shabnam Imannezhad, Mohsen Akhondi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-01-01
Series:Reviews in Clinical Medicine
Subjects:
Online Access:https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdf
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author Ali Rahdari
Reza Jalaeian Taghaddomi
Alireza Sabzevari
Shabnam Imannezhad
Mohsen Akhondi
author_facet Ali Rahdari
Reza Jalaeian Taghaddomi
Alireza Sabzevari
Shabnam Imannezhad
Mohsen Akhondi
author_sort Ali Rahdari
collection DOAJ
description Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature during cardiopulmonary surgery is not certainly detected. This systematic review has investigated the differences between hypothermia and normothermia regarding postoperative mortality. Method: PubMed was searched for the relevant articles. Only English language articles were included with no time limitation. Data regarding in-hospital patient deaths provided in each article mostly within 30 days after the surgery, were extracted and compared based on relative risk reduction (RRR), absolute risk reduction (ARR), and number needed to treat (NNT).Result: Totally, 28 articles were retrieved and extracted. The mortality rate was zero in hypothermic and normotehrmic groups of 8/28 included studies, thus the RRR, ARR, and NNT could not be calculated. There were no significant differences between investigated groups of each included studies regarding the patients’ age, gender, and preoperative conditions.Conclusions: No significant difference was obtained between two studied groups. Similar prevalence of death observed between hypothermic and normothermic groups might be due to the sample size of studies, or the subsequent cares performed in intensive care units that assist to reduce the postoperative mortality rate. According to the obtained results, both of these procedures might be similarly safe regarding mortality rate.
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spelling doaj.art-7025fca0afce4ee88fcd0af77d734aa32022-12-27T13:10:46ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922016-01-0131323810.17463/RCM.2016.01.0086028Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypassAli Rahdari0Reza Jalaeian Taghaddomi1Alireza Sabzevari2Shabnam Imannezhad3Mohsen Akhondi4Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Gynecology, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature during cardiopulmonary surgery is not certainly detected. This systematic review has investigated the differences between hypothermia and normothermia regarding postoperative mortality. Method: PubMed was searched for the relevant articles. Only English language articles were included with no time limitation. Data regarding in-hospital patient deaths provided in each article mostly within 30 days after the surgery, were extracted and compared based on relative risk reduction (RRR), absolute risk reduction (ARR), and number needed to treat (NNT).Result: Totally, 28 articles were retrieved and extracted. The mortality rate was zero in hypothermic and normotehrmic groups of 8/28 included studies, thus the RRR, ARR, and NNT could not be calculated. There were no significant differences between investigated groups of each included studies regarding the patients’ age, gender, and preoperative conditions.Conclusions: No significant difference was obtained between two studied groups. Similar prevalence of death observed between hypothermic and normothermic groups might be due to the sample size of studies, or the subsequent cares performed in intensive care units that assist to reduce the postoperative mortality rate. According to the obtained results, both of these procedures might be similarly safe regarding mortality rate.https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdfcardiopulmonary bypasshypothermianormothermia
spellingShingle Ali Rahdari
Reza Jalaeian Taghaddomi
Alireza Sabzevari
Shabnam Imannezhad
Mohsen Akhondi
Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
Reviews in Clinical Medicine
cardiopulmonary bypass
hypothermia
normothermia
title Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
title_full Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
title_fullStr Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
title_full_unstemmed Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
title_short Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
title_sort hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
topic cardiopulmonary bypass
hypothermia
normothermia
url https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdf
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