Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature du...
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Mashhad University of Medical Sciences
2016-01-01
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Series: | Reviews in Clinical Medicine |
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Online Access: | https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdf |
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author | Ali Rahdari Reza Jalaeian Taghaddomi Alireza Sabzevari Shabnam Imannezhad Mohsen Akhondi |
author_facet | Ali Rahdari Reza Jalaeian Taghaddomi Alireza Sabzevari Shabnam Imannezhad Mohsen Akhondi |
author_sort | Ali Rahdari |
collection | DOAJ |
description | Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature during cardiopulmonary surgery is not certainly detected. This systematic review has investigated the differences between hypothermia and normothermia regarding postoperative mortality. Method: PubMed was searched for the relevant articles. Only English language articles were included with no time limitation. Data regarding in-hospital patient deaths provided in each article mostly within 30 days after the surgery, were extracted and compared based on relative risk reduction (RRR), absolute risk reduction (ARR), and number needed to treat (NNT).Result: Totally, 28 articles were retrieved and extracted. The mortality rate was zero in hypothermic and normotehrmic groups of 8/28 included studies, thus the RRR, ARR, and NNT could not be calculated. There were no significant differences between investigated groups of each included studies regarding the patients’ age, gender, and preoperative conditions.Conclusions: No significant difference was obtained between two studied groups. Similar prevalence of death observed between hypothermic and normothermic groups might be due to the sample size of studies, or the subsequent cares performed in intensive care units that assist to reduce the postoperative mortality rate. According to the obtained results, both of these procedures might be similarly safe regarding mortality rate. |
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issn | 2345-6256 2345-6892 |
language | English |
last_indexed | 2024-04-11T04:45:36Z |
publishDate | 2016-01-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Reviews in Clinical Medicine |
spelling | doaj.art-7025fca0afce4ee88fcd0af77d734aa32022-12-27T13:10:46ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922016-01-0131323810.17463/RCM.2016.01.0086028Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypassAli Rahdari0Reza Jalaeian Taghaddomi1Alireza Sabzevari2Shabnam Imannezhad3Mohsen Akhondi4Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Gynecology, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Cardiopulmonary bypass is associated with higher risk of mortality and morbidity, thus it should be investigated regarding the major risk factors. Temperature management have a significant role in postoperative cerebral and neurological complications; however the optimum temperature during cardiopulmonary surgery is not certainly detected. This systematic review has investigated the differences between hypothermia and normothermia regarding postoperative mortality. Method: PubMed was searched for the relevant articles. Only English language articles were included with no time limitation. Data regarding in-hospital patient deaths provided in each article mostly within 30 days after the surgery, were extracted and compared based on relative risk reduction (RRR), absolute risk reduction (ARR), and number needed to treat (NNT).Result: Totally, 28 articles were retrieved and extracted. The mortality rate was zero in hypothermic and normotehrmic groups of 8/28 included studies, thus the RRR, ARR, and NNT could not be calculated. There were no significant differences between investigated groups of each included studies regarding the patients’ age, gender, and preoperative conditions.Conclusions: No significant difference was obtained between two studied groups. Similar prevalence of death observed between hypothermic and normothermic groups might be due to the sample size of studies, or the subsequent cares performed in intensive care units that assist to reduce the postoperative mortality rate. According to the obtained results, both of these procedures might be similarly safe regarding mortality rate.https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdfcardiopulmonary bypasshypothermianormothermia |
spellingShingle | Ali Rahdari Reza Jalaeian Taghaddomi Alireza Sabzevari Shabnam Imannezhad Mohsen Akhondi Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass Reviews in Clinical Medicine cardiopulmonary bypass hypothermia normothermia |
title | Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
title_full | Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
title_fullStr | Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
title_full_unstemmed | Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
title_short | Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
title_sort | hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass |
topic | cardiopulmonary bypass hypothermia normothermia |
url | https://rcm.mums.ac.ir/article_6028_70938fa8b5834a89abf184f3ba00d435.pdf |
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