Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens

The effect of dietary lipids and Clostridium butyricum supplementation on circulating lipids and the transcription of selected genes involved in lipid metabolism were investigated in broiler chickens. One hundred and sixty-day-old broilers (Arbor Acres) were divided into four treatment groups in a 2...

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Main Authors: B. Zhang, X. Yang, Y. Guo, F. Long
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Animal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731111001066
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author B. Zhang
X. Yang
Y. Guo
F. Long
author_facet B. Zhang
X. Yang
Y. Guo
F. Long
author_sort B. Zhang
collection DOAJ
description The effect of dietary lipids and Clostridium butyricum supplementation on circulating lipids and the transcription of selected genes involved in lipid metabolism were investigated in broiler chickens. One hundred and sixty-day-old broilers (Arbor Acres) were divided into four treatment groups in a 2 × 2 factorial arrangement and fed four diets with two lipid sources (soybean oil or fish oil) and two levels of C. butyricum (0 or 5 g/kg) for a period of 6 weeks. Serum concentrations of total cholesterol and low-density lipoprotein cholesterol were lower (P < 0.05) in broilers fed diets containing fish oil than in those fed diets containing soybean oil. Fish oil significantly reduced (P < 0.05) hepatic fatty acid synthase and lipoprotein lipase (LPL) activities in abdominal fat. In contrast, fish oil significantly increased (P < 0.05) breast muscle LPL activity and hepatic peroxisome proliferator-activated receptor-α and LPL gene expression. The addition of C. butyricum significantly increased (P < 0.05) LPL activity in abdominal fat and liver-type fatty acid-binding protein gene expression in jejunal mucosa. The results of this study indicated that the reduced abdominal fat in broilers fed fish oil as observed may be due to augmented hepatic fatty acid catabolism and lower hepatic fat synthesis. The increased intramuscular fat content in breast muscle of broilers fed C. butyricum as described may be the result of enhanced fatty acid uptake.
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spelling doaj.art-70269f2cb07c440bbb88a3c4eb7fd0a82022-12-21T19:18:44ZengElsevierAnimal1751-73112011-01-0151219091915Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickensB. Zhang0X. Yang1Y. Guo2F. Long3State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, PR ChinaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, PR China; State Key Laboratory of Biological Feed Engineering, Beijing Dabeinong Technology Group Co. Ltd, Beijing, ChinaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, PR ChinaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, PR ChinaThe effect of dietary lipids and Clostridium butyricum supplementation on circulating lipids and the transcription of selected genes involved in lipid metabolism were investigated in broiler chickens. One hundred and sixty-day-old broilers (Arbor Acres) were divided into four treatment groups in a 2 × 2 factorial arrangement and fed four diets with two lipid sources (soybean oil or fish oil) and two levels of C. butyricum (0 or 5 g/kg) for a period of 6 weeks. Serum concentrations of total cholesterol and low-density lipoprotein cholesterol were lower (P < 0.05) in broilers fed diets containing fish oil than in those fed diets containing soybean oil. Fish oil significantly reduced (P < 0.05) hepatic fatty acid synthase and lipoprotein lipase (LPL) activities in abdominal fat. In contrast, fish oil significantly increased (P < 0.05) breast muscle LPL activity and hepatic peroxisome proliferator-activated receptor-α and LPL gene expression. The addition of C. butyricum significantly increased (P < 0.05) LPL activity in abdominal fat and liver-type fatty acid-binding protein gene expression in jejunal mucosa. The results of this study indicated that the reduced abdominal fat in broilers fed fish oil as observed may be due to augmented hepatic fatty acid catabolism and lower hepatic fat synthesis. The increased intramuscular fat content in breast muscle of broilers fed C. butyricum as described may be the result of enhanced fatty acid uptake.http://www.sciencedirect.com/science/article/pii/S1751731111001066Clostridium butyricumfish oillipid-related genes expressionbroiler chicken
spellingShingle B. Zhang
X. Yang
Y. Guo
F. Long
Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
Animal
Clostridium butyricum
fish oil
lipid-related genes expression
broiler chicken
title Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
title_full Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
title_fullStr Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
title_full_unstemmed Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
title_short Effects of dietary lipids and Clostridium butyricum on serum lipids and lipid-related gene expression in broiler chickens
title_sort effects of dietary lipids and clostridium butyricum on serum lipids and lipid related gene expression in broiler chickens
topic Clostridium butyricum
fish oil
lipid-related genes expression
broiler chicken
url http://www.sciencedirect.com/science/article/pii/S1751731111001066
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