Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication
Intravesical Bacillus Calmette-Guérin (BCG) immunotherapy for non-muscle invasive bladder cancer (NMIBC) has been used as a treatment since 1976. It is effective in reducing disease recurrence and progression, with mostly self-limiting or mild side effects. Serious complications are rare and thought...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442022000158 |
| _version_ | 1819121438766923776 |
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| author | Katherine Ong John Dyer Moira Wilson Dickon Hayne |
| author_facet | Katherine Ong John Dyer Moira Wilson Dickon Hayne |
| author_sort | Katherine Ong |
| collection | DOAJ |
| description | Intravesical Bacillus Calmette-Guérin (BCG) immunotherapy for non-muscle invasive bladder cancer (NMIBC) has been used as a treatment since 1976. It is effective in reducing disease recurrence and progression, with mostly self-limiting or mild side effects. Serious complications are rare and thought to be either related to systemic BCG infection (BCG-osis) or a systemic inflammatory response, and often require systemic anti-tuberculous therapy. We report a rare case of urethral fistulation leading to perineal BCG-abscess during intravesical BCG immunotherapy for high grade bladder cancer. This ultimately required systemic anti-tuberculous therapy and cessation of intravesical BCG treatment. |
| first_indexed | 2024-12-22T06:36:34Z |
| format | Article |
| id | doaj.art-702aa946c9fd4b04be6d52cff4427b48 |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-22T06:36:34Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-702aa946c9fd4b04be6d52cff4427b482022-12-21T18:35:33ZengElsevierUrology Case Reports2214-44202022-05-0142102003Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complicationKatherine Ong0John Dyer1Moira Wilson2Dickon Hayne3Department of Urology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; Corresponding author. U 609/9 Tully Road, East Perth, 6004, Western Australia, Australia.Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, Western Australia, AustraliaDepartment of Infectious Diseases, Fiona Stanley Hospital, Murdoch, Western Australia, AustraliaDepartment of Urology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; UWA Medical School, University of Western Australia, Crawley, Western Australia, Australia; Australia and New Zealand Urogenital and Prostate (ANZUP) Cancer Trials Group, Sydney, New South Wales, AustraliaIntravesical Bacillus Calmette-Guérin (BCG) immunotherapy for non-muscle invasive bladder cancer (NMIBC) has been used as a treatment since 1976. It is effective in reducing disease recurrence and progression, with mostly self-limiting or mild side effects. Serious complications are rare and thought to be either related to systemic BCG infection (BCG-osis) or a systemic inflammatory response, and often require systemic anti-tuberculous therapy. We report a rare case of urethral fistulation leading to perineal BCG-abscess during intravesical BCG immunotherapy for high grade bladder cancer. This ultimately required systemic anti-tuberculous therapy and cessation of intravesical BCG treatment.http://www.sciencedirect.com/science/article/pii/S2214442022000158Bacillus Calmette-GuérinBladder cancerPerineal collectionPerineal abscessBCG complicationsIntravesical BCG |
| spellingShingle | Katherine Ong John Dyer Moira Wilson Dickon Hayne Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication Urology Case Reports Bacillus Calmette-Guérin Bladder cancer Perineal collection Perineal abscess BCG complications Intravesical BCG |
| title | Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication |
| title_full | Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication |
| title_fullStr | Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication |
| title_full_unstemmed | Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication |
| title_short | Urethral fistula and perineal collection during intravesical treatment for non-muscle invasive bladder cancer – A rare complication |
| title_sort | urethral fistula and perineal collection during intravesical treatment for non muscle invasive bladder cancer a rare complication |
| topic | Bacillus Calmette-Guérin Bladder cancer Perineal collection Perineal abscess BCG complications Intravesical BCG |
| url | http://www.sciencedirect.com/science/article/pii/S2214442022000158 |
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