Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome
Abstract Introduction Atrial fibrillation (AF) is the leading cause of ischemic stroke and is one of the most common arrhythmias. Previous studies have shown that impaired diastolic functions, P wave dispersion (Pd), and prolonged atrial conduction times (ACT) are associated with increased incidence...
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | Advances in Rheumatology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42358-020-0112-6 |
| _version_ | 1818557170966331392 |
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| author | Hasan Akkaya Ertuğrul Emre Güntürk Ercan Kaydok Betül Özdemir |
| author_facet | Hasan Akkaya Ertuğrul Emre Güntürk Ercan Kaydok Betül Özdemir |
| author_sort | Hasan Akkaya |
| collection | DOAJ |
| description | Abstract Introduction Atrial fibrillation (AF) is the leading cause of ischemic stroke and is one of the most common arrhythmias. Previous studies have shown that impaired diastolic functions, P wave dispersion (Pd), and prolonged atrial conduction times (ACT) are associated with increased incidence of atrial fibrillation (AF). The aim of this study was to evaluate diastolic functions, Pd, and ACT in fibromyalgia syndrome (FMS) patients to determine whether there is an increase in the risk of developing AF. Methods The study included a total of 140 female patients (70 FMS group, 70 healthy control group). Pd was evaluated using 12 lead electrocardiography (ECG), and diastolic functions and ACT with echocardiography. The ECG and echocardiographic evaluations were performed by different cardiologists blinded to the clinical information of the subjects. Results There was no difference between the two groups in laboratory and clinical parameters. Patients with FMS had significantly higher echocardiographic parameters of ACT known as left-sided intra-atrial (13.9 ± 5.9 vs. 8.1 ± 1.8, p < 0.001), right-sided intra-atrial (21.9 ± 8.2 vs. 10.4 ± 3.5, p < 0.001) and interatrial [40 (25–64) ms vs. 23 (14–27) ms p < 0.001] electromechanical interval (EMI) compared with the control group. Pd was significantly greater in the FMS group compared with the control group [46 (29–62) ms vs. 32 (25–37) ms, p < 0.001]. In the FMS group, there was no significant relationship of the echocardiographic parameters of ACT, Pmax and Pd with age, E/A ratio and deceleration time (DT); while all these five parameters were significantly correlated with left atrial dimension, isovolumetric relaxation time (IVRT), fibromyalgia impact questionnaire (FIQ) and visual analogue scale (VAS). There was a strong correlation between FIQ and VAS and echocardiographic parameters of ACT, Pmax and Pd. Conclusions Impaired diastolic functions, an increase in Pd, and prolongation of ACT were observed in FMS. Current disorders are thought to be associated with an increased risk of AF in FMS. The risk of developing AF increases with the severity of FMS and clinical progression. |
| first_indexed | 2024-12-13T23:56:28Z |
| format | Article |
| id | doaj.art-702e7e73ccae49958cf933c4280d76b5 |
| institution | Directory Open Access Journal |
| issn | 2523-3106 |
| language | English |
| last_indexed | 2024-12-13T23:56:28Z |
| publishDate | 2020-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Advances in Rheumatology |
| spelling | doaj.art-702e7e73ccae49958cf933c4280d76b52022-12-21T23:26:31ZengBMCAdvances in Rheumatology2523-31062020-01-016011610.1186/s42358-020-0112-6Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndromeHasan Akkaya0Ertuğrul Emre Güntürk1Ercan Kaydok2Betül Özdemir3Cardiology Department, Niğde Ömer Halisdemir University Medicine Faculty Education and Research HospitalCardiology Department, Niğde Ömer Halisdemir University Medicine Faculty Education and Research HospitalPhysical Medicine and Rehabilitation Department, Niğde Ömer Halisdemir University Medicine Faculty Education and Research HospitalCardiology Department, Niğde Ömer Halisdemir University Medicine Faculty Education and Research HospitalAbstract Introduction Atrial fibrillation (AF) is the leading cause of ischemic stroke and is one of the most common arrhythmias. Previous studies have shown that impaired diastolic functions, P wave dispersion (Pd), and prolonged atrial conduction times (ACT) are associated with increased incidence of atrial fibrillation (AF). The aim of this study was to evaluate diastolic functions, Pd, and ACT in fibromyalgia syndrome (FMS) patients to determine whether there is an increase in the risk of developing AF. Methods The study included a total of 140 female patients (70 FMS group, 70 healthy control group). Pd was evaluated using 12 lead electrocardiography (ECG), and diastolic functions and ACT with echocardiography. The ECG and echocardiographic evaluations were performed by different cardiologists blinded to the clinical information of the subjects. Results There was no difference between the two groups in laboratory and clinical parameters. Patients with FMS had significantly higher echocardiographic parameters of ACT known as left-sided intra-atrial (13.9 ± 5.9 vs. 8.1 ± 1.8, p < 0.001), right-sided intra-atrial (21.9 ± 8.2 vs. 10.4 ± 3.5, p < 0.001) and interatrial [40 (25–64) ms vs. 23 (14–27) ms p < 0.001] electromechanical interval (EMI) compared with the control group. Pd was significantly greater in the FMS group compared with the control group [46 (29–62) ms vs. 32 (25–37) ms, p < 0.001]. In the FMS group, there was no significant relationship of the echocardiographic parameters of ACT, Pmax and Pd with age, E/A ratio and deceleration time (DT); while all these five parameters were significantly correlated with left atrial dimension, isovolumetric relaxation time (IVRT), fibromyalgia impact questionnaire (FIQ) and visual analogue scale (VAS). There was a strong correlation between FIQ and VAS and echocardiographic parameters of ACT, Pmax and Pd. Conclusions Impaired diastolic functions, an increase in Pd, and prolongation of ACT were observed in FMS. Current disorders are thought to be associated with an increased risk of AF in FMS. The risk of developing AF increases with the severity of FMS and clinical progression.https://doi.org/10.1186/s42358-020-0112-6Fibromyalgia syndromeAtrial fibrillationImpaired diastolic functionsP wave dispersionProlongation of atrial electromechanical interval |
| spellingShingle | Hasan Akkaya Ertuğrul Emre Güntürk Ercan Kaydok Betül Özdemir Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome Advances in Rheumatology Fibromyalgia syndrome Atrial fibrillation Impaired diastolic functions P wave dispersion Prolongation of atrial electromechanical interval |
| title | Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| title_full | Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| title_fullStr | Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| title_full_unstemmed | Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| title_short | Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| title_sort | determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome |
| topic | Fibromyalgia syndrome Atrial fibrillation Impaired diastolic functions P wave dispersion Prolongation of atrial electromechanical interval |
| url | https://doi.org/10.1186/s42358-020-0112-6 |
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