Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia

Despite hyperglycemia has been associated to breast cancer, the underlying mechanisms are not completely understood. Here, the authors show that epigenetic regulation of Nrg1 gene during hyperglycemia promotes breast cancer development.

Bibliographic Details
Main Authors: Changhu Lee, Min Kim, Chanho Park, Woobeen Jo, Jeong Kon Seo, Sahee Kim, Jiyoung Oh, Chu-Sook Kim, Han Suk Ryu, Kyung-Hun Lee, Jiyoung Park
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36179-8
Description
Summary:Despite hyperglycemia has been associated to breast cancer, the underlying mechanisms are not completely understood. Here, the authors show that epigenetic regulation of Nrg1 gene during hyperglycemia promotes breast cancer development.
ISSN:2041-1723