ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes

ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes

Abstract Pancreatic β-cell loss through apoptosis is an important disease mechanism in type 2 diabetes. Apoptosis Repressor with CARD (ARC) is a cell death inhibitor that antagonizes multiple death programs. We previously reported that ARC is abundant in pancreatic β-cells and modulates survival of...

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Bibliographic Details
Main Authors:	Wendy M. McKimpson, Min Zheng, Streamson C. Chua, Jeffrey E. Pessin, Richard N. Kitsis
Format:	Article
Language:	English
Published:	Nature Portfolio 2017-08-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-07107-w

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