Cellular Lipids—Hijacked Victims of Viruses
Over the millions of years-long co-evolution with their hosts, viruses have evolved plenty of mechanisms through which they are able to escape cellular anti-viral defenses and utilize cellular pathways and organelles for replication and production of infectious virions. In recent years, it has becom...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/14/9/1896 |
| _version_ | 1797481421409878016 |
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| author | Bozena Omasta Jana Tomaskova |
| author_facet | Bozena Omasta Jana Tomaskova |
| author_sort | Bozena Omasta |
| collection | DOAJ |
| description | Over the millions of years-long co-evolution with their hosts, viruses have evolved plenty of mechanisms through which they are able to escape cellular anti-viral defenses and utilize cellular pathways and organelles for replication and production of infectious virions. In recent years, it has become clear that lipids play an important role during viral replication. Viruses use cellular lipids in a variety of ways throughout their life cycle. They not only physically interact with cellular membranes but also alter cellular lipid metabolic pathways and lipid composition to create an optimal replication environment. This review focuses on examples of how different viruses exploit cellular lipids in different cellular compartments during their life cycles. |
| first_indexed | 2024-03-09T22:14:20Z |
| format | Article |
| id | doaj.art-7037c3a91735491fb9c8ca0cd6ee5726 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T22:14:20Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-7037c3a91735491fb9c8ca0cd6ee57262023-11-23T19:26:01ZengMDPI AGViruses1999-49152022-08-01149189610.3390/v14091896Cellular Lipids—Hijacked Victims of VirusesBozena Omasta0Jana Tomaskova1Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, SlovakiaBiomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, SlovakiaOver the millions of years-long co-evolution with their hosts, viruses have evolved plenty of mechanisms through which they are able to escape cellular anti-viral defenses and utilize cellular pathways and organelles for replication and production of infectious virions. In recent years, it has become clear that lipids play an important role during viral replication. Viruses use cellular lipids in a variety of ways throughout their life cycle. They not only physically interact with cellular membranes but also alter cellular lipid metabolic pathways and lipid composition to create an optimal replication environment. This review focuses on examples of how different viruses exploit cellular lipids in different cellular compartments during their life cycles.https://www.mdpi.com/1999-4915/14/9/1896lipidsvirusvirus–host interactioncholesterolmetabolism |
| spellingShingle | Bozena Omasta Jana Tomaskova Cellular Lipids—Hijacked Victims of Viruses Viruses lipids virus virus–host interaction cholesterol metabolism |
| title | Cellular Lipids—Hijacked Victims of Viruses |
| title_full | Cellular Lipids—Hijacked Victims of Viruses |
| title_fullStr | Cellular Lipids—Hijacked Victims of Viruses |
| title_full_unstemmed | Cellular Lipids—Hijacked Victims of Viruses |
| title_short | Cellular Lipids—Hijacked Victims of Viruses |
| title_sort | cellular lipids hijacked victims of viruses |
| topic | lipids virus virus–host interaction cholesterol metabolism |
| url | https://www.mdpi.com/1999-4915/14/9/1896 |
| work_keys_str_mv | AT bozenaomasta cellularlipidshijackedvictimsofviruses AT janatomaskova cellularlipidshijackedvictimsofviruses |