Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature

Purpose. To report the acute development of hypopyon after primary cryopreserved amniotic membrane transplantation (AMT) for persistent corneal epithelial defect and sterile ulceration. Case Presentation. A selected case report of a 71-year-old male who underwent primary cryopreserved AMT for the ma...

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Main Authors: Kostas G. Boboridis, Dimitrios G. Mikropoulos, Nick S. Georgiadis
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/9982354
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author Kostas G. Boboridis
Dimitrios G. Mikropoulos
Nick S. Georgiadis
author_facet Kostas G. Boboridis
Dimitrios G. Mikropoulos
Nick S. Georgiadis
author_sort Kostas G. Boboridis
collection DOAJ
description Purpose. To report the acute development of hypopyon after primary cryopreserved amniotic membrane transplantation (AMT) for persistent corneal epithelial defect and sterile ulceration. Case Presentation. A selected case report of a 71-year-old male who underwent primary cryopreserved AMT for the management of long-standing corneal epithelial defects and stroma thinning. The patient developed 2 mm sterile hypopyon within 48 hours after AMT for corneal surface reconstruction. He responded well to the intensified routine postoperative topical treatment of steroid and antibiotic eye drops with the hypopyon resolving completely one week later. Five weeks after surgery, the corneal surface was smooth and epithelialized with no anterior chamber reaction or recurrence of hypopyon. Discussion. Hypopyon may develop as a rare complication of primary cryopreserved AMT for sterile corneal defects. It may be attributed to immunologic or hypersensitivity reaction and should be differentiated from active ocular infection as it resolves spontaneously with the routine postoperative topical treatment of steroid and antibiotic drops.
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spelling doaj.art-703a8b3ce3d34cd5858ed30ef2b989ea2022-12-22T04:05:41ZengHindawi LimitedCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/99823549982354Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the LiteratureKostas G. Boboridis0Dimitrios G. Mikropoulos1Nick S. Georgiadis23rd Ophthalmology Department, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki 546 21, Greece3rd Ophthalmology Department, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki 546 21, Greece3rd Ophthalmology Department, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki 546 21, GreecePurpose. To report the acute development of hypopyon after primary cryopreserved amniotic membrane transplantation (AMT) for persistent corneal epithelial defect and sterile ulceration. Case Presentation. A selected case report of a 71-year-old male who underwent primary cryopreserved AMT for the management of long-standing corneal epithelial defects and stroma thinning. The patient developed 2 mm sterile hypopyon within 48 hours after AMT for corneal surface reconstruction. He responded well to the intensified routine postoperative topical treatment of steroid and antibiotic eye drops with the hypopyon resolving completely one week later. Five weeks after surgery, the corneal surface was smooth and epithelialized with no anterior chamber reaction or recurrence of hypopyon. Discussion. Hypopyon may develop as a rare complication of primary cryopreserved AMT for sterile corneal defects. It may be attributed to immunologic or hypersensitivity reaction and should be differentiated from active ocular infection as it resolves spontaneously with the routine postoperative topical treatment of steroid and antibiotic drops.http://dx.doi.org/10.1155/2021/9982354
spellingShingle Kostas G. Boboridis
Dimitrios G. Mikropoulos
Nick S. Georgiadis
Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
Case Reports in Ophthalmological Medicine
title Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
title_full Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
title_fullStr Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
title_full_unstemmed Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
title_short Hypopyon after Primary Cryopreserved Amniotic Membrane Transplantation for Sterile Corneal Ulceration: A Case Report and Review of the Literature
title_sort hypopyon after primary cryopreserved amniotic membrane transplantation for sterile corneal ulceration a case report and review of the literature
url http://dx.doi.org/10.1155/2021/9982354
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