Targeted Demethylation of the TGFβ1 mRNA Promotes Myoblast Proliferation via Activating the SMAD2 Signaling Pathway

Targeted Demethylation of the TGFβ1 mRNA Promotes Myoblast Proliferation via Activating the SMAD2 Signaling Pathway

Recent evidence suggested that N6-methyladenosine (m<sup>6</sup>A) methylation can determine m<sup>6</sup>A-modified mRNA fate and play an important role in skeletal muscle development. It was well known that transforming growth factor beta 1 (TGFβ1) is involved in a variety...

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Bibliographic Details
Main Authors: Kaiping Deng, Zhipeng Liu, Xiaodan Li, Zhen Zhang, Yixuan Fan, Qunhao Huang, Yanli Zhang, Feng Wang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
m<sup>6</sup>A
dCas13b
TGFβ1
cell proliferation
myoblast
Online Access:https://www.mdpi.com/2073-4409/12/7/1005

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