Dexmedetomidine attenuates persistent postsurgical pain by upregulating K+–Cl− cotransporter-2 in the spinal dorsal horn in rats

Dexmedetomidine attenuates persistent postsurgical pain by upregulating K+–Cl− cotransporter-2 in the spinal dorsal horn in rats

Shuhong Dai,1 Yu Qi,1 Jie Fu,1 Na Li,1 Xu Zhang,1 Juan Zhang,2 Wei Zhang,2 Haijun Xu,1 Hai Zhou,1 Zhengliang Ma2 1Department of Anesthesiology, XuZhou Central Hospital, Xuzhou, China; 2The Affiliated Nanjing Drum Tower Hospital, Medical School, Nanjing University, Nanjing, China Background: Dexmedet...

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Bibliographic Details
Main Authors: Dai S, Qi Y, Fu J, Li N, Zhang X, Zhang J, Zhang W, Xu H, Zhou H, Ma Z
Format: Article
Language:English
Published: Dove Medical Press 2018-05-01
Series:Journal of Pain Research
Subjects:
Skin/muscle incision and retraction
persistent postsurgical pain
dexmedetomidine
KCC2
BDNF/trkB signal
Online Access:https://www.dovepress.com/dexmedetomidine-attenuates-persistent-postsurgical-pain-by-upregulatin-peer-reviewed-article-JPR

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