Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness

Background Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is more than 0.02 cc for dermal hydration. Clinically, this is an excessive amount for this purpose, so I will...

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Main Author: Jongseo Kim
Format: Article
Language:English
Published: Korean Society for Aesthetic Plastic Surgery 2014-06-01
Series:Archives of Aesthetic Plastic Surgery
Subjects:
Online Access:http://e-aaps.org/upload/pdf/aaps-20-97.pdf
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author Jongseo Kim
author_facet Jongseo Kim
author_sort Jongseo Kim
collection DOAJ
description Background Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is more than 0.02 cc for dermal hydration. Clinically, this is an excessive amount for this purpose, so I will introduce a modified method using particle type S-HA injection for dermal hydration. Methods One hundred fifty patients who had 1,000 injections of 1 cc S-HA by injector were analyzed. The patients were examined after 1, 2, 6, 12, and 24 months. Changes in skin texture were determined with regard to skin roughness and morphology, dermal hydration by electric resistance, dermal thickness by ultrasonic imaging, and biopsy. An intra-individual study was also performed to compare changes in skin texture between dermal and subdermal injections. Results Skin roughness significantly improved after this procedure. Electric resistance also decreased. The dermis of the face and hand were thickened about 4% after dermal injection. The injection depth was confirmed by biopsy. There were no significant changes in dermal thickness after subdermal injection with S-HA, which merely replaced fluid volume. Injections into the dermis changed both skin texture and thickness. Conclusions Skin texture was improved after 1000 dermal injections (0.001 cc each) of particle type S-HA. Deeper injections only replaced the fluid volume and could not improve skin texture. For this purpose, the use of an injector or mesogun is recommended.
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spelling doaj.art-704186741cd1456aaed0b57475d64a8b2022-12-21T18:10:00ZengKorean Society for Aesthetic Plastic SurgeryArchives of Aesthetic Plastic Surgery2234-08312288-93372014-06-012029710310.14730/aaps.2014.20.2.97126Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and ThicknessJongseo KimBackground Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is more than 0.02 cc for dermal hydration. Clinically, this is an excessive amount for this purpose, so I will introduce a modified method using particle type S-HA injection for dermal hydration. Methods One hundred fifty patients who had 1,000 injections of 1 cc S-HA by injector were analyzed. The patients were examined after 1, 2, 6, 12, and 24 months. Changes in skin texture were determined with regard to skin roughness and morphology, dermal hydration by electric resistance, dermal thickness by ultrasonic imaging, and biopsy. An intra-individual study was also performed to compare changes in skin texture between dermal and subdermal injections. Results Skin roughness significantly improved after this procedure. Electric resistance also decreased. The dermis of the face and hand were thickened about 4% after dermal injection. The injection depth was confirmed by biopsy. There were no significant changes in dermal thickness after subdermal injection with S-HA, which merely replaced fluid volume. Injections into the dermis changed both skin texture and thickness. Conclusions Skin texture was improved after 1000 dermal injections (0.001 cc each) of particle type S-HA. Deeper injections only replaced the fluid volume and could not improve skin texture. For this purpose, the use of an injector or mesogun is recommended.http://e-aaps.org/upload/pdf/aaps-20-97.pdfhyaluronic acidintradermal injectionsmicroinjectionssubcutaneous hydration
spellingShingle Jongseo Kim
Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
Archives of Aesthetic Plastic Surgery
hyaluronic acid
intradermal injections
microinjections
subcutaneous hydration
title Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
title_full Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
title_fullStr Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
title_full_unstemmed Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
title_short Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness
title_sort effects of injection depth and volume of stabilized hyaluronic acid in human dermis on skin texture hydration and thickness
topic hyaluronic acid
intradermal injections
microinjections
subcutaneous hydration
url http://e-aaps.org/upload/pdf/aaps-20-97.pdf
work_keys_str_mv AT jongseokim effectsofinjectiondepthandvolumeofstabilizedhyaluronicacidinhumandermisonskintexturehydrationandthickness