Imaging TCR-Dependent NFAT-Mediated T-Cell Activation with Positron Emission Tomography In Vivo

Imaging TCR-Dependent NFAT-Mediated T-Cell Activation with Positron Emission Tomography In Vivo

A noninvasive method for molecular imaging of T-cell activity in vivo would be of considerable value. It would aid in understanding the role of specific genes and signal transduction pathways in the course of normal and pathologic immune responses, could elucidate temporal dynamics and immune regula...

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Bibliographic Details
Main Authors: Vladimir Ponomarev, Michael Doubrovin, Clay Lyddane, Tatiana Beresten, Julius Balatoni, William Bornman, Ronald Finn, Timothy Akhurst, Steven Larson, Ronald Blasberg, Michel Sadelain, Juri Gelovani Tjuvajev
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
molecular imaging
T- cell activation
herpes virus type 1 thymidine kinase
FIAU
PET
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800038

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