Development of a Promising Method for Producing Oligomeric Mixture of Branched Alkylene Guanidines to Improve Substance Quality and Evaluate Their Antiviral Activity against SARS-CoV-2

Development of a Promising Method for Producing Oligomeric Mixture of Branched Alkylene Guanidines to Improve Substance Quality and Evaluate Their Antiviral Activity against SARS-CoV-2

This paper reports the synthesis of branched alkylene guanidines using microfluidic technologies. We describe the preparation of guanidine derivatives at lower temperatures, and with significantly less time than that required in the previously applicable method. Furthermore, the use of microfluidics...

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Bibliographic Details
Main Authors: Denis O. Shatalov, Stanislav A. Kedik, Ivan S. Ivanov, Anna V. Aydakova, Diana A. Akhmedova, Dmitrii S. Minenkov, Sergei V. Beliakov, Alexander Herbst, Lasse Greiner, Liubov I. Kozlovskaya, Viktor P. Volok
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
antiseptic
microfluidics
microreactor
polycondensation
antimicrobial resistance
antiviral activity
Online Access:https://www.mdpi.com/1420-3049/26/11/3472

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