Gut Microbiome and Metabonomic Profile Predict Early Remission to Anti-Integrin Therapy in Patients with Moderate to Severe Ulcerative Colitis

Gut Microbiome and Metabonomic Profile Predict Early Remission to Anti-Integrin Therapy in Patients with Moderate to Severe Ulcerative Colitis

ABSTRACT Patients with ulcerative colitis (UC) have low response rates to anti-integrin medications, necessitating the identification of noninvasive biomarkers for predicting remission to anti-integrin therapy. In this study, patients with moderate to severe UC commencing anti-integrin therapy (n = ...

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Bibliographic Details
Main Authors: Jie Liu, Huaying Fang, Na Hong, Chaolan Lv, Qihua Zhu, Yinping Feng, Bo Wang, Jiashuang Tian, Yue Yu
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
anti-integrin therapy
metabonomics
microbiology
ulcerative colitis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01457-23

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