Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands
Invasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully i...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kerman University of Medical Sciences
2015-11-01
|
| Series: | International Journal of Health Policy and Management |
| Subjects: | |
| Online Access: | http://www.ijhpm.com/pdf_3095_417156a045b5a30bd898b5334db8e98d.html |
| _version_ | 1817978474341597184 |
|---|---|
| author | Josefien Cornelie Minthe Bousema Joost Ruitenberg |
| author_facet | Josefien Cornelie Minthe Bousema Joost Ruitenberg |
| author_sort | Josefien Cornelie Minthe Bousema |
| collection | DOAJ |
| description | Invasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully implemented a single dose of meningococcal serogroup C conjugate vaccine at the age of 14 months and performed a single catch-up for children ≤18 years of age. Since then the disease disappeared in vaccinated individuals. Furthermore, herd protection was induced, leading to a significant IMD reduction in non-vaccinated individuals. However, previous studies revealed that the current programmatic immunisation strategy was insufficient to protect the population in the foreseeable future. In addition, vaccines that provide protection against additional serogroups are now available. This paper describes to what extent the current strategy to prevent IMD in the Netherlands is still sufficient, taking into account the burden of disease and the latest scientific knowledge related to IMD and its prevention. In particular, primary MenC immunisation seems not to provide long-term protection, indicating a risk for possible recurrence of the disease. This can be combatted by implementing a MenC or MenACWY adolescent booster vaccine. Additional health benefits can be achieved by replacing the primary MenC by a MenACWY vaccine. By implementation of a recently licensed MenB vaccine for infants in the NIP, the greatest burden of disease would be targeted. This paper shows that optimisation of the immunisation strategy targeting IMD in the Netherlands should be considered and contributes to create awareness concerning prevention optimisation in other countries. |
| first_indexed | 2024-04-13T22:30:46Z |
| format | Article |
| id | doaj.art-70473fe61e1c4fffae844aa73581d3b1 |
| institution | Directory Open Access Journal |
| issn | 2322-5939 2322-5939 |
| language | English |
| last_indexed | 2024-04-13T22:30:46Z |
| publishDate | 2015-11-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | International Journal of Health Policy and Management |
| spelling | doaj.art-70473fe61e1c4fffae844aa73581d3b12022-12-22T02:26:56ZengKerman University of Medical SciencesInternational Journal of Health Policy and Management2322-59392322-59392015-11-0141175776110.15171/ijhpm.2015.168Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the NetherlandsJosefien Cornelie Minthe Bousema0 Joost Ruitenberg1Athena Institute, Faculty of Earth and Life Sciences, VU University, Amsterdam, The NetherlandsAthena Institute, Faculty of Earth and Life Sciences, VU University, Amsterdam, The NetherlandsInvasive meningococcal disease (IMD) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. In recent years, industrialised countries have implemented vaccines targeting IMD in their National Immunisation Programmes (NIPs). In 2002, the Netherlands successfully implemented a single dose of meningococcal serogroup C conjugate vaccine at the age of 14 months and performed a single catch-up for children ≤18 years of age. Since then the disease disappeared in vaccinated individuals. Furthermore, herd protection was induced, leading to a significant IMD reduction in non-vaccinated individuals. However, previous studies revealed that the current programmatic immunisation strategy was insufficient to protect the population in the foreseeable future. In addition, vaccines that provide protection against additional serogroups are now available. This paper describes to what extent the current strategy to prevent IMD in the Netherlands is still sufficient, taking into account the burden of disease and the latest scientific knowledge related to IMD and its prevention. In particular, primary MenC immunisation seems not to provide long-term protection, indicating a risk for possible recurrence of the disease. This can be combatted by implementing a MenC or MenACWY adolescent booster vaccine. Additional health benefits can be achieved by replacing the primary MenC by a MenACWY vaccine. By implementation of a recently licensed MenB vaccine for infants in the NIP, the greatest burden of disease would be targeted. This paper shows that optimisation of the immunisation strategy targeting IMD in the Netherlands should be considered and contributes to create awareness concerning prevention optimisation in other countries.http://www.ijhpm.com/pdf_3095_417156a045b5a30bd898b5334db8e98d.htmlImmunisationInvasive Meningococcal Disease (IMD)National Immunisation Programme (NIP)PreventionPublic HealthVaccines |
| spellingShingle | Josefien Cornelie Minthe Bousema Joost Ruitenberg Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands International Journal of Health Policy and Management Immunisation Invasive Meningococcal Disease (IMD) National Immunisation Programme (NIP) Prevention Public Health Vaccines |
| title | Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands |
| title_full | Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands |
| title_fullStr | Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands |
| title_full_unstemmed | Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands |
| title_short | Need for Optimisation of Immunisation Strategies Targeting Invasive Meningococcal Disease in the Netherlands |
| title_sort | need for optimisation of immunisation strategies targeting invasive meningococcal disease in the netherlands |
| topic | Immunisation Invasive Meningococcal Disease (IMD) National Immunisation Programme (NIP) Prevention Public Health Vaccines |
| url | http://www.ijhpm.com/pdf_3095_417156a045b5a30bd898b5334db8e98d.html |
| work_keys_str_mv | AT josefiencornelieminthebousema needforoptimisationofimmunisationstrategiestargetinginvasivemeningococcaldiseaseinthenetherlands AT joostruitenberg needforoptimisationofimmunisationstrategiestargetinginvasivemeningococcaldiseaseinthenetherlands |