Radiological, pathological and surgical outcomes after neoadjuvant endocrine treatment in patients with ER-positive/HER2-negative breast cancer with a clinical high risk and a low-risk 70-gene signature

Radiological, pathological and surgical outcomes after neoadjuvant endocrine treatment in patients with ER-positive/HER2-negative breast cancer with a clinical high risk and a low-risk 70-gene signature

Objective: This study aims to evaluate the response to and surgical benefits of neoadjuvant endocrine therapy (NET) in ER+/HER2-breast cancer patients who are clinically high risk, but genomic low risk according to the 70-gene signature (MammaPrint). Methods: Patients with ER+/HER2-invasive breast c...

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Bibliographic Details
Main Authors: Josefien P. van Olmen, Chaja F. Jacobs, Sanne A.L. Bartels, Claudette E. Loo, Joyce Sanders, Marie-Jeanne T.F.D. Vrancken Peeters, Caroline A. Drukker, Frederieke H. van Duijnhoven, Marleen Kok
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Breast
Subjects:
ER+/HER2-breast cancer
Neoadjuvant treatment
Endocrine therapy
70-Gene signature
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977624000572

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http://www.sciencedirect.com/science/article/pii/S0960977624000572

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