Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease
AIM: To elucidate the state and importance of the calcium-regulating system, calcium and phosphorus balances, their impact on ulcer activity, regional microcirculation, and hemostasis during recurrent peptic ulcer disease (PUD)/MATERIAL AND METHODS: Sixty patients with recurrent PUD were examined. T...
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2014-02-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31421 |
| _version_ | 1818777911078944768 |
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| author | L A Fomina |
| author_facet | L A Fomina |
| author_sort | L A Fomina |
| collection | DOAJ |
| description | AIM: To elucidate the state and importance of the calcium-regulating system, calcium and phosphorus balances, their impact on ulcer activity, regional microcirculation, and hemostasis during recurrent peptic ulcer disease (PUD)/MATERIAL AND METHODS: Sixty patients with recurrent PUD were examined. They underwent determinations of blood parathyrin and calcitonin and blood and urinary calcium and phosphorus levels and studies of regional microcirculation in the gastroduodenal mucosa and systemic hemostatic parameters in addition to clinical and endoscopic examinations/RESULTS: Recurrent PUD is accompanied by a significant blood parathyrin rise and some calcitonin increase and by calcium-phosphorus imbalance. Impaired calcium-regulating system functions attend significant microcirculatory disorders in the gastroduodenal mucosa and hemostatic changes characteristic of consumptive coagulopathy/CONCLUSION: A clear relationship between calcium-regulating hormone impairments, calcium and phosphorus metabolism with ulcer activity and microcirculatory and hemostatic changes may suggest the found shifts in ulcerogenesis and the pathogenetic substantiation of correction of these disorders may be of importance for the treatment of a disease recurrence. |
| first_indexed | 2024-12-18T11:36:21Z |
| format | Article |
| id | doaj.art-704b25aa1f4c49c8b890830a15ff2447 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-18T11:36:21Z |
| publishDate | 2014-02-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-704b25aa1f4c49c8b890830a15ff24472022-12-21T21:09:30Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422014-02-01862131628437Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer diseaseL A FominaAIM: To elucidate the state and importance of the calcium-regulating system, calcium and phosphorus balances, their impact on ulcer activity, regional microcirculation, and hemostasis during recurrent peptic ulcer disease (PUD)/MATERIAL AND METHODS: Sixty patients with recurrent PUD were examined. They underwent determinations of blood parathyrin and calcitonin and blood and urinary calcium and phosphorus levels and studies of regional microcirculation in the gastroduodenal mucosa and systemic hemostatic parameters in addition to clinical and endoscopic examinations/RESULTS: Recurrent PUD is accompanied by a significant blood parathyrin rise and some calcitonin increase and by calcium-phosphorus imbalance. Impaired calcium-regulating system functions attend significant microcirculatory disorders in the gastroduodenal mucosa and hemostatic changes characteristic of consumptive coagulopathy/CONCLUSION: A clear relationship between calcium-regulating hormone impairments, calcium and phosphorus metabolism with ulcer activity and microcirculatory and hemostatic changes may suggest the found shifts in ulcerogenesis and the pathogenetic substantiation of correction of these disorders may be of importance for the treatment of a disease recurrence.https://ter-arkhiv.ru/0040-3660/article/view/31421peptic ulcer diseasecalcium-regulating systemcalciumphosphorusmicrocirculationhemostasis |
| spellingShingle | L A Fomina Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease Терапевтический архив peptic ulcer disease calcium-regulating system calcium phosphorus microcirculation hemostasis |
| title | Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| title_full | Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| title_fullStr | Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| title_full_unstemmed | Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| title_short | Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| title_sort | value of the calcium regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease |
| topic | peptic ulcer disease calcium-regulating system calcium phosphorus microcirculation hemostasis |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31421 |
| work_keys_str_mv | AT lafomina valueofthecalciumregulatingsysteminthedevelopmentofmicrocirculatoryandhemostaticdisordersinrecurrentpepticulcerdisease |